Incorporating of silica nanoparticles with crown ethers is interest regarding the excellent stability these inorganic polymers against various acidic and basic conditions. The attachments to macrocycles are involved many reactions attach active site ether modified nanoparticles. To achieve goal, selection 3,5-dihydroxybenzolic acid as a model for synthesis macrocycle base reaction esterificatio...

The reaction of Pb[BF(4)](2) in H(2)O/MeCN solution with the macrocycle 18-crown-6 gave the dinuclear complex [{Pb(18-crown-6)(H(2)O)(μ(2)-BF(4))}(2)][BF(4)](2), containing two nine-coordinate lead centres, each bound to all six oxygens of a crown ligand, one water molecule and bridged by two μ(2)-BF(4) groups. In contrast, the oxa-thia crown [18]aneO(4)S(2) gave the mononuclear [Pb([18]aneO(4)...

The pH- and chemically-driven unidirectional transport of a macrocycle through [2]rotaxane based on the vinyl sulfonyl groups is reported.

The structures of a number of mono- and diboron corrole complexes have been optimized using DFT methods in order to establish regio- and stereochemical preferences for bonding of one or two boron atoms to the corrole macrocycle. The formulations of the complexes were suggested either from preliminary experimental results (to be reported elsewhere) or by analogy with related diboron porphyrin co...

Many vitally im portan t functions in living systems are carried out by metal ions held as complexes within organic ligands, the organic p a rt of the molecule being a te trapyrrolic macrocycle. Chlorophyll, haemoglobin, the cytochromes and vitam in B12 all fall into this family of ‘pigm ents of life’, a list th a t emphasizes their central im portance in living systems. Research on the biosynt...

12-Aza-epothilones (azathilones) incorporating quinoline side chains and bearing different N12-substituents have been synthesized via highly efficient RCM-based macrocyclizations. Quinoline-based azathilones with the side chain N-atom in the meta-position to the C15 atom in the macrocycle are highly potent inhibitors of cancer cell growth in vitro. In contrast, shifting the quinoline nitrogen t...

The structural and reactive properties of the acetyl-protected "one-legged" manganese porphyrin [SAc]P-Mn(III)Cl on Ag(100) have been studied by NEXAFS, synchrotron XPS and STM. Spontaneous surface-mediated deprotection occurs at 300 K accompanied by spreading of the resulting thio-tethered porphyrin across the metal surface. Loss of the axial chlorine ligand occurs at 498 K, without any demeta...