BACKGROUND The extracellular domain of the HER-2/neu oncogene product is increased in sera of some patients with epithelial cancers. Our aim was to develop an automated serum assay for the extracellular domain of the HER-2/neu protein. METHODS We used a monoclonal antibody labeled with fluorescein for capture and a monoclonal Fab' fragment labeled with alkaline phosphatase for detection. Sepa...

Cell Separation and Protein PuriTcation (1996) Oslo, Norway: Dynal. 165 pp. HaK feli U, SchuK tt W, Teller J and ZborowskiM (eds) (1997) ScientiTc and Clinical Applications of Magnetic Carriers. New York: Plenum Press. Olsvik ", Popovic T, Skjerve E et al. (1994) Magnetic separation techniques in diagnostic microbiology. Clinical Microbiology Reviews 7: 43d54. Recktenwald D and Radbruch A (eds)...

Cancer is a leading cause of death worldwide and it is caused by the interaction of genomic, environmental, and lifestyle factors. Although chemotherapy is one way of treating cancers, it also damages healthy cells and may cause severe side effects. Therefore, it is beneficial in drug delivery in the human body to increase the proportion of the drugs at the target site while limiting its exposu...

In magnetic drug delivery, therapeutic magnetizable particles are typically injected into the blood stream and magnets are then used to concentrate them to disease locations. The behavior of such particles in-vivo is complex and is governed by blood convection, diffusion (in blood and in tissue), extravasation, and the applied magnetic fields. Using physical first-principles and a sophisticated...

The kinetics of aggregation of non Brownian magnetizable particles in the presence of a magnetic field is studied both theoretically and by means of computer simulations. Theoretical approach is based on a system of Smoluchowski equations for the distribution function of the number of particles in linear chain-like aggregates. Results obtained in the two dimensional (2D) and three dimensional (...

water soluble amphoteric graft copolymers of polysaccharide were synthesized via grafting of cationic monomer onto the sodium carboxymethylcellulose ()cmc)( and then used as a shale stabilizer in the water-based drilling fluids. accordingly, five types of cmc-graft copolymers with different ratios of acrylamide am)( and diallyldimethylammonium chloride dadmac)( were synthesized. grafting of mon...

in this work, the characteristics of flow and heat transfer of a fluid containing nano particles of aluminum oxide with the water volume fraction (0.1-0.2-0.3)(v/v) percent of the reports. the overall heat transfer coefficient, heat transfer and the average heat transfer fluid containing nano water - aluminum oxide in a horizontal double pipe counter flow heat exchanger under turbulent flow con...

in this paper, nonlinear vibration and instability response of an embedded pipe conveying viscose fluid is investigated. the pipe is considered as a timoshenko beam embedded on an elastic foundation which is simulated by spring constant of the winkler-model and the shear constant of the pasternak-model. the external flow force, acting on the beam in the direction of the flexural displacement is...

effects of some thermo-physical parameters on free convective heat and mass transfer over a vertical stretching surface at lowest level of heat energy in the presence of suction is investigated. the viscosity of the fluid is assumed to vary as a linear function of temperature and thermal conductivity is assumed constant. a similarity transformation is applied to reduce the governing equations i...