Neuropeptide S (NPS) exerts robust anxiolytic and memory enhancing effects, but only in a non-social context. In order to study whether NPS affects aggressive behavior we used Wistar rats bred for low (LAB) and high (HAB) levels of innate anxiety-related behavior, respectively, which were both described to display increased levels of aggression compared with Wistar rats not selectively bred for...

Background: Sedentary lifestyle and lack of exercise cause cardiovascular diseases metabolic syndrome. Decreased movement in recent decades has caused diseases. Methods: In this research, 35 male Wistar rats weighing 220 ± 20 g were divided into 5 groups (seven each group) by a simple random method. The first second experimental given 100 grams per liter fructose with water for 6 weeks, the thi...

Muscle fatigue is a condition resulting from prolonged muscle contractions. Synthetic materials are often used to restore fatigue, although they can have side effects. Soybean natural product that contains complex compounds, including thiamine, which has the potential replace synthetic compounds. The current study was aimed analyze effect of Glycine max on structure tissue/muscle and lactic aci...

Origanum compactum Benth. has been widely used in moroccan traditional medicine for various therapeutic treatments. Belonging to the same genus, O. onites was found have marked analgesic and anti-inflammatory activities. The aim of this work is evaluate theses pharmacological properties essential oil order provide a basis folkloric use plant. Aerial parts plant were subjected steam distillation...

Lesion of posterodorsal amygdala (PDA) has been known to produce hyperphagia and obesity in animal models. However, the influence of gender on food intake (FI), body weight (BW) and immunological parameters following PDA lesion is not yet known. The present work was carried out to study the effect of gender on the regulation of FI, BW and immunological parameters following lesions of PDA in alb...

BACKGROUND Fructose is widely used as a food ingredient and has potential to increase oxidative stress. Moreover, the beneficial health effects of medicinal plants are frequently attributed to their potent antioxidant effects. OBJECTIVES The present study was aimed to explore the effects of garlic (Allium sativum) extract on insulin resistance, inflammation and oxidative stress in male wistar...

The incidence and range of spontaneous central nervous system tumors were determined in control Charles River rodents (Sprague-Dawley, Han-Wistar, Wistar rats, and CD-1 mice) from regulatory carcinogenicity studies carried out over the period 2002 to 2013 and were compared with the previously published data. In both species, the brain was notably more affected than the spinal cord. Incidences w...

BACKGROUND Different strains of rats have been used to study alcoholic liver disease (ALD) while the reason for selecting a particular rat strain was not apparent. PURPOSE The aim of our study was to compare outbred (Wistar) and inbred (Fischer) strains to evaluate pathological, biochemical changes, and gene expression differences associated with ethanol-induced early hepatic steatosis. STU...

Our previous experiments have shown that adult male Wistar rats can differ systematically in elevated plus-maze (EPM) behaviour, which was related to the neurotransmitter serotonin in the ventral striatum. The EPM serves as a model of anxiety-like behaviour, and there is evidence that interleukin (IL)-2 in the brain may be related to anxiety-like behaviour, and that IL-2 interacts with the stri...

Anemia is a medical condition when the concentration of hemoglobin, erythrocytes, or hematocrit less than average. The peels white dragon fruit contains iron, vitamin C and flavonoids, which play an essential role as hemoglobin production. These flavonoids can increase erythropoiesis (erythrocyte formation process) have immunostimulant effects. This research aimed to analyze effect giving peel ...