Proliferating eukaryotic cells undergo a finite number of cell divisions before irreversibly exiting mitosis. Yet pathways that normally limit the number of cell divisions remain poorly characterized. Here we describe a screen of a collection of 3762 single gene mutants in the yeast Saccharomyces cerevisiae, accounting for 2/3 of annotated yeast ORFs, to search for mutants that undergo an atypi...

Previous publications have shown that BRI1 EMS suppressor 1 (BES1), a positive regulator of the brassinosteroid (BR) signalling pathway, enhances cell divisions in the quiescent centre (QC) and stimulates columella stem cell differentiation. Here, it is demonstrated that BZR1, a BES1 homologue, also promotes cell divisions in the QC, but it suppresses columella stem cell differentiation, opposi...

Although fair value is not a new measurement attribute, the interest of discussing fair value has been aroused by the release of new accounting standards. This article decodes fair value measurement again from four aspects respectively. Fair value measurement attribute is for asset measurement in the end, a kind of initiative measurement from master-slave relationship. As a matter of fact, fair...

This paper examines the nature and characteristics of the ownership relationship between objects in an object-oriented database. The ownership relationship is distinguished from the Part-Whole relationship since these two are often confused. Dimensions of the ownership relationship are detailed and described with clarifying examples from the financial securities markets. These dimensions are: 1...

The problem studied in this paper arises from a simple practical problem: how to divide a cake among the children attending a birthday p a r t y i n s u c h a way that each c hild gets the same amount o f c a k e and (perhaps more important to them) the same amount of icing. Let S be a convex set contained in the (xx y)-plane. In mathematical terms, a c a k e C with base S is a solid containing...

Prostacyclin (PGI2) appears to be synthesized in the lungs of man and experimental animals. It has been stated that PGI2 must be regarded as a local hormone that inhibits platelet adhesion to vessel walls only very close to the site of synthesis. The wide range of normal values given for PGI2 may be related to the sensitivity and exclusiveness of the different assay techniques used. In animals ...

my lab group members, and many others for useful conversations. Do not quote or circulate without permission. 1 " The besetting fallacy of writers on economic method has been justly said to be the fallacy of exclusiveness. A single aspect or department of economic study is alone kept in view, and the method appropriate thereto aggrandized, while other methods, of equal importance in their prope...

This paper examines the nature and characteristics of the ownership relationship between objects in an object-oriented database. The ownership relationship is distinguished from the Part-Whole relationship since these two are often confused. Dimensions of the ownership relationship are detailed and described with clarifying examples from the nancial securities markets. These dimensions are: 1) ...

In a model of evolution driven by con ict between societies more powerful states have an advantage. When the in uence of outsiders is small we show that this results in a tendency to hegemony. In a simple example in which institutions di er in their exclusiveness we nd that these hegemonies will be ine ciently extractive in the sense of having ine ciently high taxes, high compensation for state...