PURPOSE To quantify spatial and temporal inflammation-induced changes in vascular permeability and macrophage infiltration in guinea-pig (GP) cochlea using MRI. MATERIALS AND METHODS GPs were injected with lipopolysaccharide (LPS) to induce cochlear inflammation. One group was injected with a gadolinium based contrast agent (GBCA) and dynamic contrast enhanced (DCE)-MRI was performed at 4, 7,...

Objective: Previous studies indicated anti-inflammatory effects for Portulaca oleracea in various inflammatory disorders. In this study, the effects of P. oleracea on bronchoalveolar lavage fluid (BALF) levels of total protein (TP), Phospholipase A2(PLA2) and IgE in sensitized rats were examined. Materials and Methods: Male rats were randomly divided into six groups namely, control (group C), s...

From April 1983 to September 1990, 32 patients with familial mediterranean fever (FMF) were studied. FMF is characterized by short, self-limited, febrile episodes that occur with inflammation of serosal surfaces. Major symptoms include fever and abdominal pain, presenting as acute surgical abdomen. These attacks are associated with considerable morbidity and in some patients lead to unnece...

c-reactive protein (crp) is an acute-phase protein synthesized predominantly by the hepatocytes in response to tissue damage or inflammation. levels of acute-phase proteins rise rapidly, during infection and after injury. we take up the study to correlate serum crp levels with other important predictive markers of outcome in copd. patient with stable copd (no exacerbation in the last two months...

background : it has been suggested that inflammatory state due to obesity can lead to alteration in iron metabolism. women in reproductive age are at higher risk of iron deficiency. in this study, we aimed to evaluate inflammatory status and iron markers in young overweight and obese women. subjects and methods: in this study, 120 young and healthy women with a bmi ≥ 25 kg/m2 were enrolled. bio...