BACKGROUND Knee cartilage defects may play an important role in early osteoarthritis, but little is known about their natural history. METHODS Knee cartilage defect score (range, 0-4), cartilage volume, and bone surface area were determined using T1-weighted fat-saturated magnetic resonance imaging in 325 subjects (mean age, 45 years) at baseline and 2 years later. RESULTS Thirty-three perc...

Figure 1. Intraoperative view of left foot showing the tumor on the third toe (top left). Low-powered view of mass showing well-circumscribed tumor and pseudoencapsulation (top right). Medium-powered view of mass showing bland morphology of cells and mucinous features (bottom left). High-powered view of mass showing bland morphology and mucinous features (bottom right). DESCRIPTION A 26-year-ol...

Coffee beans from the same origin were roasted using six time-temperature profiles, in order to identify volatile aroma compounds associated with five common roast coffee defects (light, scorched, dark, baked and underdeveloped). Thirty-seven volatile aroma compounds were selected on the basis that they had previously been identified as potent odorants of coffee and were also identified in all ...

option of defect is one of common options between sale and rent contracts, however, it has special rules and conditions in those contracts. in the sale contracts, any defect in the sold or bought thing causes the victim has option of defect but in the rent contracts, only the defect creates option of defect that causes hardship in using of goods or reducing of benefits. in the sale, defect of s...

A carbon dioxide laser was used to incise around, dissect, and remove a 2-cm intradermal mass from the left carpus of an 8-year-old, spayed female wheaten terrier. The wound was partially closed, resulting in a 3-cm diameter circular defect with extensor tendons exposed. A swine intestinal submucosa graft was utilized to cover the remaining defect. The graft was removed 5 days later, revealing ...

Choledochal cyst is an uncommon premalignant anomaly. The morphology and pathogenesis of the premalignant lesion of cholangiocarcinoma arising from the choledochal cyst has not been well described. Herein, we report a rare case of bile duct adenoma arising from choledochal cyst with anomalous union of pancreaticobiliary duct (AUPBD). 50-year-old woman was admitted to our hospital with the compl...

Three patients presented with evidence of a fatty acid oxidation disorder. Analysis of urinary organic acids by gas chromatography/mass spectrometry demonstrated the presence of medium-chain (C6-C12) dicarboxylic, 3-hydroxydicarboxylic, and 3-ketodicarboxylic acids in all three urines. 3-Ketodicarboxylic aciduria is reported for the first time here, as are the mass spectra for 3-ketosuberic, 3-...

We study localized modes in uniform one-dimensional chains of tightly packed and uniaxially compressed elastic beads in the presence of one or two light-mass impurities. For chains composed of beads of the same type, the intrinsic nonlinearity, which is caused by the Hertzian interaction of the beads, appears not to support localized, breathing modes. Consequently, the inclusion of light-mass i...

Three-dimensional integrated circuits (3D ICs) introduce wafer bonding and Through Silicon Vias (TSVs) as new modules, thus extending manufacturing requirements beyond CMOS. A 3D IC with a photosensor is taken as an example to further analyze the resulting new metrology requirements for mass production. For the wafer bond module, data on defects before and after bonding, bond interface adhesion...