background: numerous studies have evaluated the association between the angiotensinogen (agt) t174m polymorphism and ischemic stroke(is) risk. however, the specific association is still controversial. materials and methods: in order to explore this association more deeply, we performed a meta-analysis. all of the relevant studies were identified from pubmed, embase, and chinese national knowled...

background: the aim of this study is to determine the frequency of intracranial artery stenosis in patients with acute ischemic stroke in iran. methods: a total of 169 patients with acute ischemic stroke were eligible to participate and were enrolled in this study from january 2012 to february 2013. all the patients were admitted to the nemazee ‎hospital, affiliated to shiraz university of medi...

Background: Patients with ischemic stroke and underlying Atrial Fibrillation (AF) have a high risk of recurrent embolic events. New Oral Anticoagulant (NOAC) is highly effective and reduces the risk of recurrence in AF-associated Ischemic Stroke (AFAIS). Objectives: This study aimed to determine the prescription pattern of NOAC and its determinant factors in patients with non-valvular AFAIS. ...

background: the role of estrogen and progesterone in stroke is suggested in previous studies, but yet is controversial. objectives: comparing the plasma levels of estrogen and progesterone and their ratio in ischemic stroke patients and healthy population. materials and methods: this cross-sectional comparative study was conducted from march to september of 2013. sixty-six female patients older...

Patients with renal failure have a higher risk for cerebrovascular events and silent brain damage and a higher cardiovascular mortality rate when compared with the general population. We present two cases where alteplase was used for hemodialysis patients (HP) with acute ischemic stroke (AIS). A 70-year-old Caucasian female with a 2-year history of hemodialysis was admitted with right hemipares...

Background: Cerebrovascular Accident (CVA) is the second cause of death and disability in the world. Heart failure can co-occur with CVA and increases the risk of death and disability in patients. Objectives: This study aimed to evaluate the prevalence of heart failure in patients with ischemic stroke. Materials & Methods: In this cross-sectional study, the information of patients with ischem...

stroke is a significant public health burden which absolutely requires more effective therapies. the approved treatment options for stroke including tissue plasminogen activators, antiplatelet agents and anticoagulants mainly bear antithrombotic effects. meanwhile, evolving investigational approaches such as collateral therapeutics and neuroprotective agents has thus far been attempted with equ...

background : the metabolic syndrome has known as an independent risk factor of stroke. the occurrence of this syndrome is due to genetic factors and lifestyle. this study was performed   on the frequency of metabolic syndrome prevalence in ischemic stroke patients compare to control. methods : one hundred ischemic stroke patients and 100 controls (with the same age and sex) were evaluated for t...

background: stroke, one of the most important causes of morbidity and mortality in the world, is of great importance in young adults (15-45 years), amongst whom the causes of stroke and transient ischemic attack (tia) are different from those in older ages and a significant portion of them have no known etiology. patent foramen ovale (pfo) is considered a probable cause in this group. methods: ...