conclusions in the children in this study, pacemaker accelerometers failed to meet physiological demands. results basal heart rates, maximal heart rates, and exercise tolerance were significantly lower in the children with pacemakers. age, sex, and body mass index had no effect on the heart rate slope during the exercise test. there was no significant difference between epicardial and endocardi...

Exercise intolerance, measured by peak oxygen consumption (V̇O2), is a hallmark feature of heart failure (HF). The effect compounded in the elderly HF patient aging-associated changes such as reduction lean muscle mass, an increase adiposity, and maximal rate peripheral blood flow with exercise. There non-linear V̇O2 age that accelerates later decades life. Peak further reduced due to central mal...

Inhibition of protein synthesis superinduces transcription of the cytochrome P1-450 gene in Hepa 1c1c7 mouse hepatoma cells. The superinduced transcription rate is 10-15-fold higher than the maximal rate of transcription induced by the known inducer 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alone. Superinduction is maximal within 30-40 min and remains maximal for at least 90 min. Cytochrome P1...

background: central obesity and hyperinsulinaemia of polycystic ovary syndrome (pcos) are associated with chronic sympathetic over activity. objective: to evaluate the autonomic functions and to indicate the superiority, if any, for those functions in the diagnosis of sympathetic over activity in pcos women. materials and methods: sixty-four pcos patients and 40 women served as the control grou...