Celiac disease is an HLA-DQ2-associated disorder characterized by intestinal T cell responses to ingested wheat gluten proteins. A peptide fragment of 33 residues (alpha(2)-gliadin 56-88) produced by normal gastrointestinal proteolysis contains six partly overlapping copies of three T cell epitopes and is a remarkably potent T cell stimulator after deamidation by tissue transglutaminase (TG2). ...

Destabilized nanobodies can be used to deliver fluorescent proteins and enzymes to specific targets inside cells.

background: potyviruses are accounted for 40% of viral diseases of various crops including vegetables and legumes. potyviruses can be transmitted through plant sap, seeds and many aphid species. due to ease of spread of these viruses detection of such viruses are crucial as to the control of the incited diseases. objectives: this study compared the efficiencies of two couples of primers in thei...

The most common technique for sorting, identifying, and purifying nucleic acid fragments is agarose gel electrophoresis. performance of the electrophoresis could be impacted by buffers’ composition, ionic strength, pH characteristics [1].

Maximum Common Induced Subgraph (MCIS) is an important NP-hard problem with wide real-world applications. An efficient class of MCIS algorithms uses Branch-and-Bound (BnB), consisting in successively selecting vertices to match and pruning when it discovered that a solution better than the best found so far does not exist. The method essential for performance BnB. In this paper, we propose new ...

Abstract We find that maximal decadal Northern Hemisphere warming increases as rapidly before after the industrial revolution (0.86 °C decade −1 1880 and 0.60–0.68 1880). However, whereas number of periods with large increase decrease rates were about equal (267 vs. 273), there are more high (35) than (9). The same patterns hold for bi-decadal rates. time windows greater 20 years, slope in glob...