Received 1/17/2005; revised 3/26/2005; accepted 4/1/2005. For correspondence or reprints contact: Chin-Ho Tsao, M.D., Division of Nuclear Medicine, Mackay Memorial Hospital, 92 Section 2, Chung-Shan North Road, Taipei 104, Taiwan. Tel: (886)2-25433535 ext. 2241, Fax: (886)2-25433535 ext. 2925, E-mail: [email protected] A 60-year-old male complained of progressing pale and jaundice in re...

AIM To evaluate the role of 99m-technetium methylene diphosphonate (Tc-99m MDP) bone scintigraphy on the detection of joint damage in asymptomatic alpine ski racers. MATERIALS AND METHODS This study included 20 male asymptomatic alpine ski racers (age range: 18-21 years). None of the skiers had a history of ski crashes. Bone scan findings of the racers were examined with Tc-99m MDP bone scint...

bone scanning using the 99mtc-phosphate analogs is an established diagnostic modality and a commonly requested radioisotope examination for a variety of pathologies involving the skeleton, such as osteomyelitis, bony metastases, and occult fractures. the bone scan is one of the most commonly requested procedure in most nuclear medicine department. the images show areas of increased and decrease...

A 58-year-old diabetic male with hepatic cirrhosis presented with fever and vague bone pains. Technetium methylene diphosphonate (Tc MDP) three phase bone scan (Figures 1 and 2) identified not only multiple sites of bone involvement but also extraskeletal renal involvement that was later proven by culture. Burkholderia pseudomallei was isolated from a blood culture, confirming a diagnosis of sy...

INTRODUCTION Prostate cancer is the second most common neoplasm among men both worldwide and in Poland. In prostate cancer, bone metastasis is related to a poorer prognosis. A diagnosis of metastatic bone disease is important in prostate cancer patients prior to therapy. Prostate specific antigen (PSA) serum value is used both as a screening tool and for staging of prostate cancer. AIM To eva...

UNLABELLED Quantitative studies of bone using (99m)Tc-methylene diphosphonate (MDP) reflect bone remodeling. The simplest method of evaluating (99m)Tc-MDP kinetics involves taking multiple blood samples and measuring total clearance (K(total)) from the area under the plasma curve (AUC) and deriving bone clearance (K(bone)) by subtracting glomerular filtration rate (GFR) from K(total). However, ...

Whole body bone scan with Technetium-99m MDP (methylene diphosphate) can detect bony lesions due to altered osteoblastic activity.Non-physiologic or increased radiotracer uptake in the bony structures of patients with a history of malignant diseases is usually interpreted as being suspicious of bone metastasis. It is extremely important to properly distinguish false positive sites of Tc-99m MDP...

A 59-year-old man presented with a 7-month history of increasing left shoulder pain. The initial plain films showed near absence of the left scapula and scattered lucent changes in the left humerus. A CT scan confirmed the presence of widespread lytic bony lesions, with a large soft-tissue mass centered around the left scapula. An isotope bone scan demonstrated marked uptake of MDP in the stoma...