T he current treatment for medulloblastoma—resection, radiation, and chemotherapy—negatively affects neurocognitive development and fails to ensure survival beyond 10 years for about 40% of children. Among the 4 molecular subtypes of this disease, the group 3 subtype has an especially poor prognosis. Recently, Bai and colleagues demonstrated compelling preclinical evidence for using the microtu...

the robert/sc (pseudothalidomide) syndrome is a rare autosomal recessive disorder, associated with phocomelia and craniofacial abnormalities. an anomalous fetus with lower limb phocomelia and micromelia, lumbar myeloschisis, upper limb and ribs defects and craniofacial abnormalities is reported whose diabetic mother took mebendazole and glibenclamide in early pregnancy. ultrasonographic finding...

Hydatidosis is a common zoonosis that affects a large number of humans and animals, especially in poorly developed countries. Mesenteric hydatid cysts are rare intra abdominal lesions with variable clinical symptoms and signs that make preoperative diagnosis diffi cult. The treatment is surgical excision followed by mebendazole for four months. We report this unusual case where preoperative dia...

Mebendazole was given to two patients with multiple hydatidosis of the liver and three patients with multiple hydatidosis of the lungs. They could not be treated surgically because of aduanced diseases. So they wer given a daily dose of 25-40 mg/kg body weight for 9-12 months. Definite clinical result in one patient and some clinical improvements in the size of the liver and clearance of the lu...