Subjective memory decline (SMD) is a heterogeneous condition. While SMD might be the earliest sign of Alzheimer's disease (AD), it also occurs in aging and various neurological, medical, and psychiatric conditions. Identifying those with higher risk to develop dementia is thus a major challenge. We tested a novel disease severity index generated by multivariate data analysis with numerous struc...

Background The Ulcerative Colitis Endoscopic Index of Severity (UCEIS) and the Mayo Endoscopic Score (MES) were developed as an objective method of the endoscopic severity in ulcerative colitis (UC); however, it was still unclear whether UCEIS vs MES could guide the need for colectomy in acute severe colitis (ASC). Methods Consecutive ASC patients between January 2012 and May 2016 were retros...

BACKGROUND Quantifying physical activity in chronic obstructive pulmonary disease (COPD) is important as physical inactivity is related to poor health outcomes. This study analyzed the relationship between patients' self-reported daily walking time and relevant characteristics related to COPD severity. METHODS Pooled analysis was performed on data from four observational studies on which dail...

OBJECTIVES Fournier's gangrene is a devastating infection, which includes the genital, perineal and/or perianal regions. It is potentially fatal, and affects any age and gender. The severity index for Fournier's gangrene has been described; it is useful for evaluating the prognosis of these patients. Our goal is to report our experience with this disease over the past 5 years and evaluate the i...

background and objective: higher concentration of systemic inflammatory markers is reported in patients with obstructive sleep apnea (osa). levels of inflammatory markers may be associated with severity of osa. objective of this study was to evaluate the correlation between level of inflammation markers and osa severity. materials and methods: fifty six patients with symptoms and signs of osa f...

conclusions: prevalence of fatty liver is high in our obese children. it was associated with criteria of metabolic syndrome and insulin resistance, so visceral fat may participate in the pathogenesis of the metabolic syndrome or merely serve as a marker of increased risk for the metabolic complications of obesity. patients and methods: 102 obese iranian children, referred to pediatric clinics f...

105 inTroducTion Civilian Tactical Emergency Medical Support (TEMS) has a long history in the United States. Enormous progress has been made during the past ten years in developing professional and operational standards within the field. However, to date, there still exists no standard of care within TEMS specifically, and more broadly for high threat pre-hospital trauma care. Current civilian ...

BACKGROUND Despite recommendations for outpatient management, low risk patients with lower respiratory tract infections (LRTIs) are often hospitalized. This survey analyzed perceptions of physicians, nurses, patients and relatives about feasibility of outpatient management and required duration of hospital stay. METHODS We performed a prospective, observational questionnaire survey in hospita...

INTRODUCTION To evaluate if the association between the BODE index and deterioration in health-related quality of life is linear. To determine possible associations between the BODE index and health status evaluated by the Saint George's Respiratory Questionnaire (SGRQ) at all levels of disease severity in COPD. METHODS A cross-sectional study was carried out on 253 patients from two Latin Am...