The market authorization procedure for medicinal products for human use is relying on their demonstrated efficacy, safety, and pharmaceutical quality. This applies to all medicinal products whether of chemical or biological origin. Since October 2009, the first advanced therapy medicinal product (ATMP) has been authorized through the centralized procedure. ATMPs are gene therapy medicinal produ...

BACKGROUND Medicinal cannabis has recently attracted much media attention in Australia and across the world. With the exception of a few countries, cannabinoids remain illegal-known for their adverse effects rather than their medicinal application and therapeutic benefit. However, there is mounting evidence demonstrating the therapeutic benefits of cannabis in alleviating neuropathic pain, impr...

BACKGROUND Fundamental in traditional postpartum recovery in Lao PDR is the use of hotbeds, mother roasting, steam sauna and steam baths. During these treatments medicinal plants play a crucial role, but little has been published about how the treatments are carried out precisely, which species are used, the medicinal properties of these species, and the medicinal efficacy of their chemical con...

involved into the modern medicinal chemist’s work. This is mainly a result of an exponential growth of the amount of data needed to be processed and analysed in the process of modern drug discovery and development. Typical tasks involved in this process include the following: ● fast access to structural and bioactivity data from the corporate database ● substructure and molecular similarity sea...

Objective: An ethnobotanical survey on the medicinal plant species marketed in Mashhad city, northeastern Iran, was conducted in order to document traditional medicinal knowledge and application of medicinal plants. Materials and Methods: This study was undertaken between 2011 and 2012. The indigenous knowledge of traditional healers used for medicinal purposes were collected through questionna...

Titanium dioxide (TiO2), a semiconducting material, is a well-known photocatalyst. A nanoparticle (NP) of TiO2 also demonstrates photocatalytic activity. Photo-irradiated TiO2 NPs induce the formation of various reactive species, leading to the damage of biomacromolecules. These reactive species include h+, either free or trapped hydroxyl radicals (OH⋅), superoxide (O2), hydrogen peroxide (H2O2...

Many studies have revealed the fact of the complexity of ontology building process. Therefore there is a need for a new approach which one of that addresses the socio-technical aspects in the collaboration to reach a consensus. Meta-design approach is considered applicable as a method in the methodological model of socio-technical ontology engineering. Principles in the meta-design framework ar...

G-Quadruplexes are special secondary structures adopted in some guanine-rich DNA sequences. The highly prevalent putative existence of G-quadruplex and the influence on genomic stability, telomere maintenance and gene expression indicate that G-quadruplexes may play important roles in biological processes [1]. Many research findings have provided substantive evidence for potential applications ...

Fenugreek is one of the well known spices in human food. Its seeds and green leaves are used in food as well as in medicinal application which is an old practice of human history. It provides natural food fibre and other nutrients required in human body [1]. Fenugreek has strong spicy and seasoning type sweet flavor [2]. Aromatic and flavourful fenugreek is a popular spice and is widely used fo...