Melasma adalah hipermelanosis tipikal di daerah wajah yang terpapar sinar ultraviolet. Gambaran klinis melasma berupa makula kecoklatan dengan tepi ireguler. Meskipun terdapat berbagai macam modalitas terapi untuk melasma, belum terbukti superior, adanya efek samping dan tingkat rekurensi tinggi. Pada pengobatan penggunaan kombinasi pendekatan baru efektif serta aman diperlukan mencapai hasil l...

Background:
 Melasma is a great challenge to the dermatologist. Choosing proper treatment and evaluation method are hard issues. Tranexamic acid [TA] injections showed promising results. The dermoscope non -invasive hand held tool
 Objective:
 To evaluate efficacy of TA in management melasma assess new dermoscopic score for assessment severity.
 Patients & Methods:
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INTRODUCTION Melasma is one of the most common pigmentary disorders seen by dermatologists and often occurs among women with darker complexion (Fitzpatrick skin type IV-VI). Even though melasma is a widely recognized cause of significant cosmetic disfigurement worldwide and in India, there is a lack of systematic and clinically usable treatment algorithms and guidelines for melasma management. ...

BACKGROUND AND OBJECTIVE A common, disfiguring problem in women, melasma is often refractory to treatment, and long-term remissions are difficult to achieve. This study assessed the safety and effectiveness of a procedure combining microdermabrasion, a topical regimen, and low fluence Q-switched Nd:YAG laser treatment. MATERIALS AND METHODS In this observational study of 27 female subjects, p...

BACKGROUND Melasma is a common skin pigment disorder with a difficult clinical response to treatment. OBJECTIVES To evaluate the clinical efficacy and safety of the association of Belides, Emblica and Licorice 7%, compared to Hydroquinone 2%, in the treatment of melasma. METHODS After 60 days of exclusive use of an SPF35 sunscreen, 56 women, 18 to 60 years of age, phototypes I to IV, with e...

BACKGROUND Melasma is a common facial skin disorder seen in women. Manual acupuncture (MA) is widely used alone or in combination with conventional treatments for melasma in China. OBJECTIVES To assess the effectiveness and safety of MA for melasma, and explore the range of treatments applied. METHODS Six databases were searched systematically for randomised controlled trials (RCTs) on acup...

INTRODUCTION Melasma/hyperpigmentation and solar damage of the skin remains a difficult problem to treat. Various types of whitening agents are used to treat hyperpigmentation. A change has been observed recently to use plant extracts as skin whitening agents. AIM To compare the effectiveness of emulsion formulations containing plant extracts that include catechins/polyphenols and placebo wit...

Although various treatment methods for melasma have developed, substantial improvement of the condition is sometimes difficult. We have experientially found that some of refractory melasma caused by daily friction can easily be treated by using a combination of a peeling agent (20% glycolic acid) and a depigmenting agent (5% hydroquinone) twice daily at home. And here, by performing skin biopsi...

This article describes a long-term, multicenter, open-label, 12-month study of once-daily fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05% (Tri-Luma Cream, hereinafter called TC [triple combination]) application in the treatment of melasma. A total of 228 patients with facial melasma were enrolled and treated; 173 patients (76%) completed the study. Most patients had 1 to 2 course...

BACKGROUND Recently, low fluence collimated Q-switched (QS) Nd:YAG laser has drawn attention for the treatment of melasma. However, it needs a lot of treatment sessions for the substantial results and repetitive laser exposures may end up with unwanted depigmentation. OBJECTIVE We evaluated the clinical effects and safety of the combinational treatment, using intense pulsed light (IPL) and lo...