A 61-year-old woman who had hypertension and diabetes presented to the gastroenterology clinic with profound fatigue and malaise of about 6 months’ duration. She denied any chest pain, shortness of breath, hematochezia, melena, hematemesis, or constitutional symptoms. The patient reported no new prescriptions, over-the-counter medications, or herbal supplements. She said that a screening colono...

Angiodysplasia describes abnormal vascular malformations found in the gastrointestinal (GI) tract, especially in the cecum and right colon. These malformations are prone to bleed and may be responsible for painless hematochezia, melena and concomitant anemia. Diagnosis can be made by direct visualization during endoscopy or angiography. Treatment consists of endoscopic interventions, including ...

A fibrovascular polyp is a rare benign disease of the upper digestive tract and is usually located in the esophagus. To our knowledge, this is the first case of gastric fibrovascular polyp presenting with melena reported in the English literature. The polyp was well visualized on endoscopy and removed with laparoscopic wedge resection. Histology confirmed fibrovascular polyp of the stomach.

Liver biopsy is the gold standard for assessment of hepatic fibrosis although it is associated with many complications. We reported a 28-year-old chronic HCV patient who developed gall bladder hematoma with hemobilia and melena after liver biopsy. The hematoma resolved with conservative management.

Angiodysplasia describes abnormal vascular malformations found in the gastrointestinal (GI) tract, especially in the cecum and right colon. These malformations are prone to bleed and may be responsible for painless hematochezia, melena and concomitant anemia. Diagnosis can be made by direct visualization during endoscopy or angiography. Treatment consists of endoscopic interventions, including ...

We report two patients that developed severe thrombocytopenia after Zika virus (ZIKV) infection. The first patient had 1000 platelets/μL and died after multiple hemorrhages. The second patient had 2000 platelets/μL, had melena and ecchymoses, and recovered after receiving intravenous immunoglobulin. ZIKV may be associated with immune-mediated severe thrombocytopenia.

Gastric disease is usually the result of inflammation, ulceration, neoplasia, or obstruction and manifests clinically as vomiting, hematemesis, melena, retching, burping, hypersalivation, abdominal distension, abdominal pain, or weight loss. The clinical approach is simplified by considering gastric diseases as a group of clinical syndromes based on the combination of etiology, pathology, and c...