Nodular regenerative hyperplasia of the liver is an uncommon disorder, the main consequence of which is portal hypertension, hepatocellular decompensation being uncommon. A case associated with membranous glomerulonephritis is reported, in which death was caused by fulminant hepatic failure.

A 3 year old boy who had chronic active hepatitis type B with features of ongoing liver damage and active virus replication, developed acute membranous glomerulonephritis two years after the clinical onset of liver disease, when both hepatitis B e antigen and antibody were detectable in serum. After withdrawal of short term steroid treatment and resolution of hepatitis B virus replication, both...

Membranous Glomerulonephritis (GMN) is an autoimmune disease whose etiology has not been defined with precisión, When there no association another which ocurrs in two thirds of the cases considered to be idiopathic. It most common cause Nephrotic Syndrome Adults, primary caucasic and over 60 years age. regarded as a non inflammatory Glomerulonephritis, concept I am completely agreement because ...

Since Grishman et al. (1967) reported organized deposits with a fingerprint pattern in kidneys with systemic lupus erythematosus (SLE), they have been regarded as a rare but special ultrastructural feature of lupus nephritis. Yet, these deposits were also described in a few cases with idiopathic membranous nephropathy (Spargo et al. 1980), membranoproliferative glomerulonephritis (MPGN) (Davis ...

Antibodies to nuclear ribonucleoprotein (nRNP), Sm, SS-A, and SS-B, were studied by a quantitative immunodiffusion technique in 48 patients with systemic lupus erythematosus (SLE). There was no correlation between the presence or titre of antibodies to any of these antigens and clinically apparent renal disease. However, among 34 patients who had renal biopsies antibodies to nRNP, Sm, and/or SS...

The serum and urine concentrations of fibrin/fibrinogen degradation products (F.D.P.) were estimated in 172 patients with glomerulonephritis. In each case the diagnosis was established on the basis of clinical, renal histological, and ultrastructural findings. Serum F.D.P. concentrations were often raised in all types of glomerulonephritis, though more consistently in active proliferative forms...

Membranous nephropathy is a common cause of nephrotic syndrome in adults and can be primary or secondary to systemic lupus erythematosus, chronic infection, or drugs. Rapid decline in renal function in patients with membranous nephropathy may be due to renal vein thrombosis, malignant hypertension, or an additional superimposed destructive process involving the renal parenchyma. Crescents are r...

BACKGROUND Mannose-binding lectin (MBL), a member of the collectin family, binds to various oligosaccharides and activates the classical pathway of complement independent from C1q. At present it is unknown whether this so-called lectin pathway of complement activation plays a role in the pathogenesis of human glomerulonephritis. METHODS Direct immunofluorescence of 84 renal biopsies using an ...