Membranous nephropathy (MN) is one of the most common biopsy diagnoses in adults, and it has been associated with chronic infections, autoimmune diseases, malignancies, and drugs. However, MN associated with cholesterol crystal emboli has never been reported. Here we present a patient with MN as an unusual manifestation of atheroembolism. A 75-year-old man with worsening renal function after ca...

BACKGROUND The diagnosis of MN is made on kidney biopsy. Diagnostic features include capillary wall thickening, normal cellularity, IgG and C3 along capillary walls on immunofluorescence, and subepithelial deposits on electron microscopy. MN is often seen in association with an underlying disorder (secondary MN). Secondary MN is more common in children (75%) than adults (25%) (Table 12). The di...

Correspondence To the Editor: Glomerulonephritis (GN) due to Mycobacterium tuberculosis (M. tuberculosis) is rare, [1] and membranous nephropathy (MN) associated with tuberculosis is seldom reported. Because of atypical and nonspecific manifestations, tuberculosis‑associated GN (TB‑GN) is difficult to diagnose. Patients usually present with hematuria, proteinuria, edema, and varying degrees of ...

Membranous nephropathy (MN) is the most common cause of adult nephrotic syndrome and it accounts for about 25% of renal biopsies done for this syndrome. Most of the cases are primary or idiopathic in nature while only about one third of the cases are secondary to some known disease.This review describes the recent advances regarding pathogenesis. Membranous nephropathy is an organ specific auto...

The patient was a 38-year-old woman diagnosed with nephrotic syndrome. Steroid pulse therapy and mizoribine was started in late October 2002 and continued for about 10 months, but no apparent therapeutic effect was obtained. During this period, the patient was diagnosed with nasopharyngeal carcinoma. As nephrotic syndrome did not improve, renal biopsy was performed and membranous nephropathy (M...

AIM To investigate vascular endothelial growth factor (VEGF) mRNA expression in glomerular disease in the context of heavy proteinuria. METHODS Non-radioisotopic in situ hybridisation was performed using a cocktail of 12 deoxyoligonucleotides complementary to VEGF mRNA labelled during solid phase synthesis with 2,4-dinitrophenyl. Archival renal biopsies were studied from cases of minimal chan...