Bariatric surgery is an effective strategy for achieving substantial weight loss, prolonging survival, and improving the comorbidities associated with obesity. Nutritional deficiency a commonly recognized post-procedural complication. Here, we present case of patient paresthesia, lower extremity weakness, altered mental status one year following Roux-en-Y gastric bypass, who was found to have m...

Vitamin D deficiency is a growing health problem in both the general population and in patients with chronic kidney disease (CKD). However, the relationship between serum 25-hydroxyvitamin D levels and health-related quality of life in CKD is not well established. This study examined the association between vitamin D deficiency and quality of life in pre-dialysis CKD patients. Serum 25-hydroxyv...

Iodine Deficiency Disorders (IDD) are one of the biggest worldwide public health problem of today. Their effect is hidden and profoundly affects the quality of human life. Iodine deficiency occurs when the soil is poor in iodine, causing a low concentration in food products and insufficient iodine intake in the population. When iodine requirements are not met, the thyroid may no longer be able ...

CONTEXT The genomic organization of the LEPR gene is complex and generates three independent transcripts whose respective functions are still poorly understood. METHODS/RESULTS We describe here a 7-year old patient with a homozygous 80 kb deletion in the chromosomal 1p31.3 region with early onset obesity, mental retardation and epilepsy. The deleted region comprises the proximal promoter and ...

The Manchester Regional Hospital Board has done a great and public-spirited service to the profession of mental nursing through fhe publication of this report of a job analysis carried out at their instigation by Mr. H. A. Goddard and his co-workers. The report comprises a detailed survey of the day to day work of the nurses of all grades in two mental deficiency hospitals and one mental hospit...

BACKGROUND Vitamin D deficiency is a re-emerging epidemic, especially in minority populations. Vitamin D is crucial not only for bone health but for proper brain development and functioning. Low levels of vitamin D are associated with depression, seasonal affective disorder, and schizophrenia in adults, but little is known about vitamin D and mental health in the pediatric population. METHODS...

Cerebral creatine deficiency syndromes (CCDSs) are a group of inborn errors of creatine metabolism comprising two autosomal recessive disorders that affect the biosynthesis of creatine--i.e. arginine:glycine amidinotransferase deficiency (AGAT; MIM 602360) and guanidinoacetate methyltransferase deficiency (GAMT; MIM 601240)--and an X-linked defect that affects the creatine transporter, SLC6A8 d...

[I submit a few facts and impressions concerning the arrangements made for mental defectives in Vienna and Berlin that a short visit enabled me to obtain.

detecting a recognizable pattern in the distribu tion of disease may be of value in respect of cause and of prevention. The recognition of classical Mendelian ratios, for instance, is both a partial explanation and an opportunity for genetic counselling which may lead relatives to take eugenic measures. In mentally sub normal populations, however, the occurrence of disease in families often sho...