TOPIC: Pulmonary Manifestations of Systemic Disease TYPE: Fellow Case Reports INTRODUCTION: Inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn's disease, are associated with a large number extraintestinal manifestations. We presenting case induced pleural disease CASE PRESENTATION: 21 y/o man history on mesalamine who presented to the clinic persistent cough. Two mon...

Three simple and sensitive visible spectrophotometric methods (A, B, and C) have been developed for the quantitative estimation of mesalamine in bulk drug and pharmaceutical dosage forms. Methods were based on the formation of colored chromogens, which were measured at 552 nm, 440 nm, and 494 nm, respectively. The results obtained with the proposed methods were found to be unsatisfactory with t...

Question: A 20-year-old male college student with a history of Crohn’s disease was noted to have pancytopenia on routine lab monitoring. He diagnosed stricturing the terminal ileum and colon over 10 years ago when he presented weight loss bloody diarrhea. struggled perianal fistulizing periodically. His Montreal classification A1 L3 B2p. Previous therapies included corticosteroids, mesalamine, ...

A 58-year-old man presented with complaints of epigastric pain for 2 years, recurrent vomiting containing stale food, and weight loss of 10 kg in the previous 3 months. He had been started on tablet mesalamine at a secondary care center for suspicion of Crohn’s disease, but there was no improvement in his symptoms. Barium meal study suggested multiple oval-shaped filling defects in his stomach ...

Background. Inflammatory bowel disease (IBD) affects patients in their young reproductive years. Women with IBD require maintenance therapies during pregnancy and breastfeeding. However, physician management of IBD during pregnancy and breastfeeding has not been well characterized. Objective. To characterize physician perceptions and management of IBD during pregnancy and breastfeeding. Methods...

INTRODUCTION Refractory coeliac disease (RCD) is a rare and severe malabsorptive disease. The condition has two subtypes: RCDI and RCDII. Different treatments have been tested: and because RCD has a poor prognosis due to progress to enteropathy-associated T-cell lymphoma, the aim was to review the epidemiologic aspects and the therapeutic options for RCD. METHODS A systematic literature searc...

WS For Crohn’s disease, mesalamine products are sometimes used, but they are not approved by the US Food and Drug Administration (FDA) and are not very effective. Corticosteroid formulations, both conventional corticosteroids and ileal-release budesonide, are effective and used for induction. Azathioprine, 6-mercaptopurine, and methotrexate are oral immunosuppressive drugs that are sometimes us...

Background & Aims Ulcerative colitis (UC) is increasingly recognized as a progressive disease and patients with long-standing can develop colorectal stricture. Few data about its incidence in UC are available, while risk factors for strictures remain to be determined. We assessed the of developing large population. Methods All adult followed at Nancy University hospital centre...