نتایج جستجو برای: mesenchymal transition
تعداد نتایج: 307477 فیلتر نتایج به سال:
BACKGROUND Despite improved survival by the addition of a monoclonal antibody against epidermal growth factor receptor (EGFR), cetuximab, to chemotherapy or radiotherapy for squamous cell carcinoma of the head and neck (SCCHN), cetuximab by itself is not a potent antiproliferative agent against SCCHN. We aimed to elucidate working mechanism of cetuximab in SCCHN. METHODS The effect of cetuxim...
Malignant melanoma is the most lethal form of skin cancer. Y-box binding protein 1 (YB-1) plays a prominent role in mediating metastatic behavior by promoting epithelial-to-mesenchymal transition (EMT). Migratory cells exhibit two major migration modes: elongated mesenchymal or rounded amoeboid. Using A375 cell line and YB-1 knock-out model, we aimed to elucidate biochemical biomechanical chang...
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