Disseminated tuberculosis in HIV infection involves multiple organs. Pulmonary and lymph node involvement are the commonest form of tuberculosis in HIV infection [1, 2]. Other forms of tuberculosis in the absence of lung and lymph node involvement are rare. Various forms of abdominal [3, 4] and neurological [5, 6] tubercular involvement in HIV infection have been reported. But tuberculosis pres...

Because the nymphal stages of L. serrata isolated from different animals have different strains, it was assumed that their somatic proteins would be different. The present study was conducted to evaluate and characterise the somatic proteins of L. serrata nymphs, isolated from goats and cattle mesenteric lymph nodes. Nymphs were collected from the infected mesenteric lymph nodes of slaughtered ...

BACKGROUND Linguatula serrata, one of the parasitic zoonoses, inhabits the canine respiratory system (final hosts). The objective of this study was to determine the prevalence rate of L. serrata nymphs in mesenteric lymph nodes (MLNs) of cattle and buffaloes (intermediate hosts) that were processed in the Ahvaz, Iran abattoir. METHODS During November 2010 to March 2011, 223 animals (119 cattl...

BACKGROUND Bortezomib is a proteasome inhibitor that has shown impressive efficacy in the treatment of multiple myeloma. In mice, the addition of dextran sulfate sodium (DSS) to drinking water leads to acute colitis that can serve as an experimental animal model for human ulcerative colitis. METHODOLOGY/PRINCIPAL FINDINGS Bortezomib treatment was shown to potently inhibit murine DSS-induced c...

Expression of high affinity IL-12 receptors is required for IL-12-mediated IFN-gamma production. Activation of this pathway has been shown to be critical in generating optimal cell-mediated immunity. Therefore, increased IL-12 receptor expression might be expected in the host response after infection by an intracellular bacterial pathogen. In the present study, we have made the surprising disco...

Red kidney beans were fed to weanling Long-Evans rats to cause diarrhoea (mean (SD) faecal wet weight: 2.66 (0.73) g/day in six rats fed beans v 1.12 (0.47) g/day in six control rats, p < 0.01) and increased faecal energy loss (4.87 (0.41) v 2.14 (0.23) kcal/day, p < 0.01). In addition, the rats fed beans had heavier small intestines (80.6 (4.6) v 51.9 (8.4) g/kg body weight, p < 0.01), heavier...

We present the case of C.I., a 16 year-old female patient, diagnosed with human immunodeficiency virus (HIV) infection since September 2006 (the suspicion beginning from a genital condylomatosis). Our patient had contact with a multidrug-resistant TBC patient (her stepmother), who abandoned the tuberculostatic therapy several times. Our patient hospitalized in December 2006, accused fever, vomi...

The surface of the intestinal mucosa is constantly assaulted by food antigens and enormous numbers of commensal microbes and their products, which are sampled by dendritic cells (DCs). Recent work shows that the mesenteric lymph nodes (MLNs) are the key site for tolerance induction to food proteins and that they also act as a firewall to prevent live commensal intestinal bacteria from penetrati...

were palpated and contained numerous hard nodules. The sigmoid colon was resected with its mesentery and lymph nodes, reconstruction was by end-to-end anastomosis with an intubated caecostomy to decompress the proximal colon. Histology of the tumour showed a well differentiated adenocarcinoma. One mesenteric lymph node contained tumour, three others examined did not. Postoperative liver function

The intestinal lymphatic system plays key roles in fluid transport, lipid absorption and immune function. Lymph flows directly from the small intestine via a series of lymphatic vessels and nodes that converge at the superior mesenteric lymph duct. Cannulation of the mesenteric lymph duct thus enables the collection of mesenteric lymph flowing from the intestine. Mesenteric lymph consists of a ...