Estrogenic activity was assessed by determining the stimulation of the uterine glycogen response of the immature rat uterus 18 hours after administration of the test compound(1). The potency of active compounds is reported in terms of the minimal subcutaneous dose which will increase glycogen to a level significantly different from control. In a series of 11 polychlorinated biphenyls and terphe...

Contact mode atomic force microscopy (AFM) was used to intentionally scratch a monolayer deposited on a pyrolyzed photoresist film (PPF). The force was set to completely remove the monolayer but not to damage the underlying PPF surface. A line profile determined across the scratch with tapping mode AFM permitted determination of the monolayer thickness from the depth of the scratch. A statistic...

The electrochemistry of m-terphenylthio-, seleno-, and telluroethers was studied using cyclic voltammetry in acetonitrile. All of the compounds studied showed irreversible oxidations. The first oxidation potentials for the thioand selenoethers are less positive than expected. This facilitation in oxidation is ascribed to through-space S···π and Se···π inter action, respectively, on removal of a...

A series of substituted diaryltriazoles was prepared by a solid-phase-synthesis protocol using a modified Wang resin. The copper(I)- or ruthenium(II)-catalyzed 1,3-cycloaddition on the polymer bead allowed a rapid synthesis of the target compounds in a parallel fashion with in many cases good to excellent yields. Substituted diaryltriazoles resemble a molecular structure similar to established ...

The antioxidant activity in vitro of three poly(phenylacetyloxy)-substituted 1,1':4',1"-terphenyl compounds from the edible mushroom Thelephora ganbajun were investigated. The IC50 values of compounds 1-3 for lipid peroxidation in rat liver homogenate were 400, 48, 54 microM, respectively. Compounds 1-3 increased superoxide dismutase (SOD) activity with EC50 values of 182, 74, 204 microM. They ...

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We study by means of molecular dynamics simulations the aging behavior of a molecular model of ortho-terphenyl. We find evidence of a nonmonotonic evolution of the volume during an isothermal-isobaric equilibration process, a phenomenon known in polymeric systems as the crossover (or Kovacs) effect. We characterize this phenomenology in terms of landscape properties, providing evidence that, fa...

In the title compound, C(28)H(19)F(2)NO(4), a polysubstituted terphenyl derivative bearing a Michael system, the C=C double bond has an E configuration. Two C-H⋯F contacts connect mol-ecules into inversion dimers. In addition, a C-H⋯π as well as a C-F⋯π contact can be identified. The shortest centroid-centroid distance between two aromatic rings is 3.9535 (8) Å, between one of the para-fluoro-b...