OBJECTIVE Bacterial trigger possibly causes disease exacerbation in enthesitis-related arthritis (ERA) patients. Microbes initiate immune responses through Toll-like receptors (TLRs). We studied TLR expression on blood and SF monocytes and the effect of TLR ligands on peripheral blood (PB) mononuclear cells (PBMCs) in ERA patients. METHODS PB from 26 ERA patients and 19 healthy subjects and p...

PURPOSE Increased bone resorption is a hallmark of multiple myeloma and is attributable to osteoclast activation. Recent studies showed that the receptor activator of nuclear factor kappaB ligand (RANKL) is the key mediator of osteoclastogenesis and plays a crucial role in bone destruction in malignant bone disease. We found that human myeloma cells express RANKL and analyzed the association of...

BACKGROUND Flow cytometry (FC) HLA-B27 typing is still used extensively for the diagnosis of spondyloarthropathies. If patient blood samples are stored for a prolonged duration, this testing can be performed in a batch manner, and in-house cellular controls could easily be procured. In this study, we investigated various methods of storing patient blood samples. METHODS WE COMPARED FOUR STORA...

A series of catalysts based on hybrid intergrowth structure zeolites MFI-MEL, MFI-MTW, and MFI-MCM-41 are studied in the reaction olefins synthesis from dimethyl ether at atmospheric pressure a temperature 340 °C. The total acidity zeolite-based is shown to correlate with their activity. However, use zeolite MFI-MCM-41, which characterized by high content medium acid sites, additionally catalyz...

This paper builds an integrated framework of measures of information based on the Model for Information (MfI) developed by the author. Since truth is expressed using information, an analysis of truth depends on the nature of information and its limitations. These limitations include those implied by the geometry of information and those implied by the relativity of information. This paper propo...

Stimulation of T cells via the CD3/TCR complex is associated with the reduced expression of accessory molecules, a phenomenon called modulation. To investigate whether the modulation is implicated in the pathogenic mechanism of pulmonary disease, we determined the MFI of CD3, CD4 and CD8 on lung and blood lymphocytes in ten normal subjects and 54 patients with various pulmonary and extrapulmona...

Modified ultrafiltration (MUF) is available for the salvage of post-cardiopulmonary bypass circuit blood. This study evaluated the extent of hemolysis, the mechanical fragility index (MFI), and the amount of plasma free hemoglobin (PFHb) created after processing with the MUF device. Several RBC parameters were measured on pre- and post-MUF device processed samples of blood from 12 patients unde...

August 17, 2000 Abstract. A research agenda is presented that focuses on the use of market principles and institutions as a micro...nance development strategy. The strategy is based on the central idea that a poverty reduction strategy can be based on the creation of employment opportunities in microand small sized enterprises (MSE) for which it is necessary to facilitate the access to credit t...

BACKGROUND Toll-like receptor (TLR)3 gene variants may correlate with clinical significance of chronic viral infections including HBV. We aimed to investigate the expression of TLR3 in peripheral blood mononuclear cells (PBMCs) and liver cells of chronic hepatitis B (CHB) patients and its response to pegylated interferon or nucleoside analogue therapy. METHODS We consecutively enrolled 127 CH...

The green microalga Chromochloris zofingiensis can accumulate significant amounts of valuable carotenoids, mainly natural astaxanthin, a product with applications in functional food, cosmetics, nutraceuticals, and with potential therapeutic value in cardiovascular and neurological diseases. To optimize the production of astaxanthin, it is essential to monitor the content of astaxanthin in algal...