OBJECTIVES To review minimally invasive parathyroidectomy (MIP) in patients undergoing initial surgical management of primary hyperparathyroidism (HPT) with preoperative, localizing sestamibi scanning (MIBI), and concordant ultrasonography (US) to determine if intraoperative parathyroid hormone (iPTH) is necessary in these cases. Minimally invasive parathyroidectomy has become an acceptable the...

We investigated the diagnostic capabilities of I-131, Tl-201, and Tc-99m-MIBI (hexakis-2-methoxyisobutyl- isonitrile) scintigraphy for thyroid cancer metastases after total thyroidectomy over the entire body and for every locus before and after thyroid bed ablation. After total thyroidectomy of thyroid cancer, 36 cases were subjected to I-131 treatment 64 times. They consisted of 17 men and 19 ...

BACKGROUND The aim of this study was to determine the diagnostic value of (99m)Tc MIBI planar dynamic scintigraphy in the diagnosis of gynaecological malignancies and to determine if it has a greater diagnostic accuracy than conventional ultrasound technique (US). MATERIAL AND METHODS A prospective trial was performed to assess the accuracy of (99m)Tc MIBI scintigraphy and ultrasound in 93 fe...

Parathyroid carcinoma is very rare, with only a few documented cases. Hence, metastatic lesions are infrequently documented on scintigraphic imaging. We present a case of a 63-year-old female presenting with elevated serum levels of ionized calcium and parathyroid hormone (PTH) who was referred to our department for a parathyroid scan with SPECT/ CT. Parathyroid scintigraphy showed a focus of i...

 Parathyroid adenoma involving a single parathyroid gland is the underlying cause of 80-85% of primary hyperparathyroidism (PHPT). Skeletal system is significantly affected by PHPT. Brown tumors are known to have affinity for 99mTc-MIBI. We report a rare case of PHPT presenting with diffuse bony pain, high calcium level and significantly elevated alkaline phosphatase level. 99m<...

Purpose: Imaging with Tc-sestamibi (Tc-MIBI) has been used to assess 170-kDa P-glycoprotein (P-gp) expression and predict chemotherapy responses in several types of malignancy, such as breast and lung cancers. The purpose of this study was to evaluate the relationship between Tc-MIBI accumulation in tumors and sensitivity to chemotherapy in gastric cancer patients. Experimental Design: Thirty-s...

BACKGROUND Primary hyperparathyroidism is caused by the excessive growth of parathormone secretion, its consequence being hypercalcemia. The parathyroid adenoma is responsible for over half of primary hyperparathyroidism cases. The mandibular tumor can be the initial sign in the case of primary hyperparathyroidism. CASE PRESENTATION We present the case of a 33 year old patient with history of...

Ectopic and/or supernumerary parathyroid glands are a major cause of persistent and recurrent Hyperparathyroidism (HPT). For this reason, it is widely accepted that preoperative localization should be performed to improve the surgical results in patients with persistent or recurrent HPT. Primary HPT (pHPT) was diagnosed incidentally in a 50-year old female patient during a preoperative examinat...