Diabetes mellitus is a group of metabolic disorders that share with symptoms hyperglycemia led to elevated free radical activity. Hyperglycemia linked higher level (ADA), which one the factors cause oxidative stress by creating reactive oxygen species (ROS), leads insulin resistance. This study aimed determine relationship between serum total adenosine deaminase(TADA) and its isoenzyme (ADA1and...

Human serum albumin (HSA) is a broadly used biomarker for the diagnosis of various diseases such as chronic kidney disease. Here, fluorescent probe TC426 with aggregation-induced emission (AIE) characteristics reported sensitive and specific HSA. This non-emissive in aqueous solution, meanwhile it shows bright fluorescence upon interacting HSA, which makes applicable detecting HSA high signal t...

of renal medulla.2 Studies in pediatric patients had revealed that renal damage starts during childhood and continues throughout life. Prolonged glomerular hyperfiltration in SCD during childhood and early adult years leads to glomerular injury, resulting in glomerular sclerosis, proteinuria, and progressive renal failure.3 Microalbuminuria is an early manifestation of sickle cell-related renal...

CASE PRESENTATION — A 26year-old woman with “brittle” type 1 diabetes and severe CAN experienced sudden cardiac death. She had a 16-year history of poor diabetes control presenting with wide blood glucose fluctuations, recurrent episodes of severe hypoglycemia, and hypoglycemia unawareness. Over time she developed persistent orthostatic hypotension with daily falls in systolic blood pressure ra...

Methods Data on children with T2DM referred to and managed in UMMC from 2000 until 2013 were collected. Their body mass index (BMI and blood tests (HbA1c and Lipids) were compared at presentation to their latest clinic appointment. Treatment modalities and duration of follow up were documented. T2DM was dignosed if they had hyperglycaemia (Random BG > 11.8mmol/L or fasting BG > 7mmol/L or 2hpp ...

The relationship between serum ascorbic acid (AA) and diabetic macroangiopathy was studied. Fifty-six patients with noninsulin-dependent diabetes mellitus were examined, together with 20 healthy controls matched for age against the diabetes patients. Aortic pulse wave velocity (PWV) was taken as an index of the severity of atherosclerosis. The level of serum AA in diabetic patients was signific...

The usefulness of bromcresol green for estimating albumin in urine was evaluated by comparison with the Laurell "rocket" technique. In contrast to the bromcresol green method applied for urinary albumin, rather doubtful results were obtained with conventional (Microzone) electrophoresis for albumin and with precipitation techniques for total protein estimation. Albumin estimation with bromcreso...