We present a microorganism-powered thermopneumatic pump that utilizes temperature-dependent slow-kinetics gas (carbon dioxide) generating fermentation of yeast as a pressure source. The pump consists of stacked layers of polydimethylsiloxane (PDMS) and a silicon substrate that form a drug reservoir, and a yeast-solution-filled working chamber. The pump operates by the displacement of a drug due...

Conventional fermentation technologies are limited due to low reactor productivity, low product yield, and low product concentration mainly due to product inhibition. There are several ways of improving the overall behavior of a biotechnological process. The cells can be modified so that the product is excreted prior to reaching inhibiting concentrations. Furthermore, a selective mutation of th...

BACKGROUND Escherichia coli is, to date, the most used microorganism for the production of recombinant proteins and biotechnologically relevant metabolites. High density cell cultures allow efficient biomass and protein yields. However, their main limitation is the accumulation of acetate as a by-product of unbalanced carbon metabolism. Increased concentrations of acetate can inhibit cellular g...

This study was carried out to determine the effects of supplementing different levels (0, 0.5 and 1% of buffered rumen fluid) of methanolic extract of pomegranate peel, on rumen fermentation kinetics of four oil seed meals (soybean meal, cotton seed meal, rapeseed meal and sunflower seed meal), using in vitro gas production technique. The samples were incubated in syringes containing rumen liqu...

The quality of the raw material for chocolate manufacture depends on control cacao seed fermentation. Practices affect diversity and metabolic activities spontaneous yeasts in fermentations. initial inoculum is important to standardize fermentations improve final quality. We conducted using non-cleaned or cleaned fermentation boxes evaluate dynamics microorganism populations their effect compos...

Microorganisms are able to produce a wide range of valuable chemicals and materials, and microbial fermentation is widely used as an alternative route for the production of chemicals in industry[1]. The key elements that determine the efficiency of a fermentation process are high titer, high yield, high productivity and process robustness[2]. These parameters are highly dependent on the host mi...

Codonopsis lanceolata (Campanulaceae) traditionally have been used as a tonic and to treat patients with lung abscesses. Recently, it was proposed that the extract and some compounds isolated from C. lanceolata reversed scopolamine-induced memory and learning deficits. The purpose of this study was to evaluate the improvement of cognitive enhancing effect of C. lanceolata by steam and fermentat...

UNLABELLED BACKGROUND The inherent recalcitrance of lignocellulosic biomass is one of the major economic hurdles for the production of fuels and chemicals from biomass. Additionally, lignin is recognized as having a negative impact on enzymatic hydrolysis of biomass, and as a result much interest has been placed on modifying the lignin pathway to improve bioconversion of lignocellulosic feed...

A newly isolated fungus Aspergillus niger SOI017 was shown to be a good producer of β-glucosidase from all isolated fungal strains. Fermentation condition (pH, cellobiose concentration, yeast extract concentration, and ammonium sulfate concentration) was optimized for producing the enzyme in shake flask cultures. Response surface methodology was used to investigate the effects of 4 fermentation...