OBJECTIVES Men presenting with primary infertility and azoospermia may be offered surgical sperm retrieval (SSR) as a prelude to intracytoplasmic sperm injection (ICSI). We evaluated sperm retrieval rates in subgroups of men with azoospermia, based on obstructive aetiology, testicular volume and FSH. METHODS 106 patients with primary infertility underwent clinical evaluation and SSR with perc...

To compare the efficacy of 2 sperm-retrieval procedures, testicular sperm extraction (TESE) and testicular sperm aspiration (TESA), during the same procedure using the same subjects as their own controls. The presence of mature testicular sperm cells and motility were evaluated in 87 men with nonobstructive azoospermia (NOA) by means of multifocal TESE and multifocal TESA, which were performed ...

background: many azoospermic patients with non obstructive azoospermia (noa) are candidate for testicular sperm extraction (tese) and in vitro fertilization. because sperm might be present in some but not all parts of the testes of such men, multiple sampling of testicular tissue are usually necessary to increase the probability of sperm finding. sperm finding can be done by two methods: 1) cla...

There is no doubt that presence of varicocele contributes to testicular atrophy and decreased fertility in men [1]. There is also evidence that varicocelectomy improved quality of sperm and improve chances of pregnancy although some randomized controlled study were less impressive [2]. Obviously not every man with a significant varicocele has fertility issues or will benefit from varicocelectom...

BACKGROUND The most common chromosomal abnormality due to non-obstructive azoospermia (NOA) is Klinefelter syndrome (KS) which occurs in 1-1.72 out of 500-1000 male infants. The probability of retrieving sperm as the outcome could be asymmetrically different between patients with and without KS, therefore logistic regression analysis is not a well-qualified test for this type of data. This stud...

background: to evaluate predictive factors of successful microdissection-testicular sperm extraction (md-tese) in patients with presumed sertoli cell-only syndrome (scos). materials and methods: in this retrospective analysis, 874 men with non-obstructive azoospermia (noa), among whom 148 individuals with diagnosis of scos in prior biopsy, underwent md-tese at department of andrology, royan ins...

Testicular sperm extraction is widely used in the treatment of male infertility in cases of non-obstructive azoospermia. Identifying spermatogenetic foci within the testes is critical for testicular sperm extraction. Two-photon laser scanning microscopy (TPLSM) is an autofluorescence-based microscopy technique that allows observation at a cellular level in the depth of fresh living tissues and ...

OBJECTIVE To investigate the impact of subinguinal microsurgical varicocelectomy on semen parameters and pregnancy outcomes in couples with male factor subfertility. DESIGN Case series. SETTING Male Infertility Clinic in an academic institution in Hong Kong. PATIENTS The clinical records of 42 consecutive subfertile male patients who had subinguinal microsurgical varicocelectomy (from Jan...

abstract: background: the availability of testis specific genes will be of help in choosing the most promising biomarkers for the detection of testicular sperm retrieval in patients with non-obstructive azoospermia (noa). cdy1 histone acetyltransferase is a histone modifier which concentrates in the nucleus of round spermatids, where histone hyperacetylation occurs and causes the replacement of...