There are conflicting reports concerning the reliability of mass isotopomer distribution analysis (MIDA) for estimating the contribution of gluconeogenesis to total glucose production (f) during [13C]glycerol infusion. 1 We have evaluated substrate-induced effects on rate of appearance (Ra) of glycerol and glucose and f during [2-13C]glycerol infusion in vivo. Five groups of mice were fasted fo...

We present CytoBrowser, an open-source (GPLv3) JavaScript and Node.js driven environment for fast accessible collaborative online visualization, assessment, annotation of very large microscopy images, including, but not limited to, z-stacks (focus stacks) cytology or histology whole slide images. CytoBrowser provides a web-based viewer high-resolution zoomable images facilitates easy rem...

A multi-gram-scale synthetic route to a novel, bifunctional normorphan 3D building block bearing orthogonally reactive vinyl MIDA boronate and N-2,4-dimethoxybenzyl (DMB) amide functional handles has been developed. Synthetic manipulation at each of the demonstrated including Suzuki-Miyaura cross-coupling, exo-diastereoselective hydrogenation, N-DMB group removal lactam reduction. Normorphan co...

Los estudios sobre calidad del trabajo han minimizado la importancia de los componentes no pecuniarios actividad laboral y centrado su atención en el análisis estratificación social, mostrando una jerarquía vertical por clases sociales, obviando las relaciones horizontales que subyacen a lógicas empleo industrial post-industrial. El objetivo este artículo es doble: presentar un índice compuesto...

En el presente artículo busca lograr la documentación y sistematización de experiencias del proceso para construcción índice competitividad en las regiones Centro Litoral Atlántico República Honduras, dentro convenio colaboración investigativa entre Instituto Investigaciones Económicas Sociales Universidad Nacional Autónoma Honduras (IIES-UNAH) Consejo Inversiones (CNI). La investigación, un “í...