Objective(s): The aim of this study was to investigate the effects of mild hypothermia on expression of NF-E2-related factor 2 (Nrf2) and heme-oxygenase-1 (HO-1) of rat cerebral cortex and hippocampus after cardiopulmonary resuscitation and further investigate the possible mechanism of action. Material and Methods:To copy an asphyxia heart arrest model, Sprague Dawley rats were randomly divided...

The relation between the subjective report of memory problems and objective evidence of the same has been debated with mixed results appearing in the literature. Less is known about the relation between objective change in test performance and the perceptions of cognitive change from family members/friends and trained clinicians. These relations were explored using 5-year longitudinal data from...

You need not look far to find a slew of articles, white papers, and research reports describing the vulnerability of voice over IP systems. VoIP systems are vulnerable, but currently, the threat of actual attack to these systems is moderate. New vulnerabilities are being reported at an accelerating rate, such as the one that recently affected Cisco’s Call Manager (http://www.techweb.com/wire/ s...

As a family physician, I often encounter patients with mild cognitive decline in my practice. The prevalence of dementia in those older than 65 years of age is 8%, meaning that an average family physician’s practice has approximately 30 to 40 elderly patients with dementia.1 As a primary care physician, it is often challenging to diagnose these patients in the early stages, as well as to ensure...

BACKGROUND Abuse of older people is a serious issue and is associated with an increased risk of morbidity and mortality, and professionals will encounter elderly victims of abuse in all areas of the health care system. An important health determinant is behavioral factors, including coping style, which will impact on how older people manage stress and maintain control in their lives, and thereb...

This study examined the relationship between phonemic and semantic (category) verbal fluency and cognitive status in the Wisconsin Registry for Alzheimer's Prevention (WRAP), a longitudinal cohort enriched for family history of Alzheimer's disease. Participants were 283 WRAP subjects (age 53.1[6.5] years at baseline); who had completed three waves of assessment, over ∼6 years and met psychometr...

The objective of our study was to assess the accuracy of the Thai version of the Addenbrooke's Cognitive Examination III (ACE-T). We used the ACE-T to assess 107 participants aged 60 or over, divided into the following groups: early dementia, n=30; mild cognitive impairment (MCI), n=29; and normal controls (NC), n=48. The ACE-T exhibited good internal consistency (0.93) and inter-rater reliabil...

This study investigated whether a motor skill learning intervention could provide better memory for personal identification numbers (PINs) as compared to a control group. Younger (ages 18 to 40) and older (ages 61 to 92) participants were randomly assigned to conditions. All participants received three days of training consisting of 12 blocks of 12 trials each. Participants were tested immediat...

OBJECTIVE To discuss the design, rationale, and implementation of an intervention development study addressing indicated and selective prevention of depression and anxiety in individuals 60 years and older with mild cognitive impairment (MCI) and in their caregivers. METHODS In Phase I, now completed, we developed and standardized problem-solving therapy (PST) and the combined PST + moderate-...

BACKGROUND In this paper we present a survey of the literature dealing with IQ stability in children with childhood autism (CA) over the last ten years. Nowadays there is no clear evidence on this topic. SUBJECTS AND METHODS We used the online "PubMed" database. By inputting the following key words: (autism and IQ and child) and (stability or outcome or follow-up) we obtained a total of 78 re...