Note: This is a only a draft version, so there could be flaws. If you find any errors, please do send email to [email protected]. A more thorough version would be available soon in this space. 1 The Gibbard–Satterthwaite Impossibility Theorem We have seen in the last section that dominant strategy incentive compatibility is an extremely desirable property of social choice functions. Howeve...

Jiahua Chen, Abbas Khalili Department of Statistics and Actuarial Science University of Waterloo Abstract A fundamental and challenging problem in the application of finite mixture models is to make inference on the order of the model. In this paper, we develop a new penalized likelihood approach to the order selection problem. The new method deviates from the information-based methods such as ...

The localization of oocyte-specific determinants in the form of mRNAs to the pro-oocyte is essential for the establishment of oocyte identity. Localization of the Bicaudal-D (Bic-D) protein to the presumptive oocyte is required for the accumulation of Bic-D and other mRNAs to the pro-oocyte. The Bic-D protein contains four well-defined heptad repeat domains characteristic of intermediate filame...

SUBSET, written in the matrix language Gauss, is a program that identifies optimal subsets of means or proportions based on independent groups. All possible configurations of ordered subsets of groups are identified and the best model is selected using either the AIC or BIC information criterion. For means, both homogeneous and heterogeneous variance cases are considered. SUBSET offers an alter...

The production of high-affinity antibodies by B cells is essential for pathogen clearance. Antibody affinity for antigen is increased through the affinity maturation in germinal centers (GCs). This is an iterative process in which B cells cycle between proliferation coupled with the acquisition of mutations and antigen-based positive selection, resulting in retention of the highest-affinity B c...

Garcinia Linn. plants having rich natural xanthones and benzophenones with anti-inflammatory activity attracted a great deal of attention to discover and develop them as potential drug candidates. Through screening targeting nitric oxide accumulation in stimulated macrophage, we found that 1,3,5,7-tetrahydroxy-8-isoprenylxanthone (TIE) had potential anti-inflammatory effect. To understand how T...