BACKGROUND Multiple sensitizations in early age have been reported to be a risk for development of asthma. This study evaluates the emergence and evolution of IgE to aeroallergens among a cohort of children with physician-diagnosed atopic dermatitis and/or showing food allergy symptoms and to examine the relation to asthma development. METHODS Three-hundred and four children (median age 13.4 ...

BACKGROUND Although cockroach (CR) is an important cause of allergic sensitization worldwide, only a few data are available in Italy and in a previous study we have observed, in Naples area, a low prevalence of CR sensitization. OBJECTIVES We sought to perform a prospective study for assessing the prevalence of allergic sensitization to CR in a sample of atopic population living in Campania d...

In patients with respiratory allergy, cross-reactivity between aeroallergens and foods may induce food allergy, symptoms ranging from oral allergy syndrome to severe anaphylaxis. Clinical entities due to IgE sensitization to cross-reactive aeroallergen and food allergen components are described for many sources of plant origin (pollen-food syndromes and associations, such as birch-apple, cypres...

Since tropomyosin is cross reactive in many arthropods, it was assumed that this highly conserved protein could be responsible for cross reactions in house dust mite (HDM) allergic patients who experienced adverse reactions after crustacean and mollusc ingestion. Here we report two clinical cases where the role of tropomyosin is a matter of debate. In the first case, the clinical history, as we...

Background Atopic Dermatitis is a disease with high prevalence in Italy (about 15% of the population). As known, Atopic Dermatitis is often associated with respiratory allergy to mite.We previously showed that sublingual immunotherapy (SLIT) to mite has a beneficial clinical effect in patients with allergic extrinsic Atopic Dermatititis (AD). To investigate the long term effects, we performed a...

make changes in their homes to reduce dust mite exposure (knowledge) and whether they had made any changes in their homes to reduce dust mite exposure (practice). Results. The study families were predominately white (50%) or African American (35%). All of the children demonstrated positive skin test results for dust mite allergen, 61% (n 69) had been examined and skin-tested by an allergist bef...

Background Allergic rhinitis is one of the most common types of rhinitis. Allergen avoidance is the most important way of preventing this disease. The present study is carried out to determine the frequency of common aeroallergens in patients with allergic rhinitis in Gorgan city by skin prick test (SPT) reactivity. Materials and Methods  In this cross-sectional study 270 patients referring t...

One of the many aspects of the relationships between parasite infections and allergic diseases is the possibility that allergens from parasites enhance the TH2 responses, especially IgE production, in allergic diseases such as asthma. In this review we discuss about the allergenic composition of the nematode Ascaris lumbricoides and their potential impact on allergy sensitization and asthma pat...

Twenty one adult patients with asthma, with positive skin test responses to the European house dust mite, Dermatophagoides pteronyssinus, were randomly allocated to a control group or to a group applying house dust mite avoidance measures. These included an initial application of liquid nitrogen to mattresses and bedroom carpets to kill the live house dust mite population. Histamine airway resp...

allergy diagnosis needs to be improved in polysensitized patients due to the existence of possible confounding factors in this type of patients. component resolved diagnosis (crd) is a new concept in the investigation of polysensitized patients. the aim of this study was to evaluate if the utilization of immunocap isac improve the diagnosis of the polysensitized allergic rhinitis patients. skin...