We investigated the evolutionary dynamics of infection of a Drosophila simulans population by a maternally inherited insect bacterial parasite, Wolbachia, by analyzing nucleotide variability in three regions of the mitochondrial genome in four infected and 35 uninfected lines. Mitochondrial variability is significantly reduced compared to a noncoding region of a nuclear-encoded gene in both uni...

Although most components of the mitochondrial translation apparatus are encoded by nuclear genes, all known molecular defects associated with impaired mitochondrial translation are due to mutations in mitochondrial DNA. We investigated two siblings with a severe defect in mitochondrial translation, reduced levels of oxidative phosphorylation complexes containing mitochondrial DNA (mtDNA)-encode...

The nuclear gene MIPl is strictly required for mitochondrial DNA replication and mitochondrial DNA polymerase activity (Genga, A., Bianchi, L., and Foury, F. (1986) J. Biol. Chem. 261,9328-9332). The MIPl gene was cloned by genetic complementation of the mipl-1 allele after cell transformation with a yeast genomic library and was mapped to the right arm of chromosome XV about 20 centimorgans d...

An extensive examination of the external and internal morphological characters genus Nychiodes shows that “ ” tyttha Prout, 1915 is incorrectly placed in this genus. The systematic position species was investigated by using a multigene analysis, including one mitochondrial up to nine protein-coding nuclear gene regions, characters. These results support re-classification as Aphilopota , comb. n...

Two new species and a record of blood sucking biting midges the subgenus Lasiohelea Kieffer, 1921 genus Forcipomyia Meigen, 1818 are described after morphological molecular data. The species. (Lasiohelea) peditata F. (L.) falcata were fetched from Sub-Himalayan region, parvitas (Liu Yu, 1996) both Gangetic plain western plateau regions West Bengal. DNA barcoding Mitochondrial COX I gene has als...

Respiratory deficient mutants of Saccharomyces cerevisiae previously assigned to complementation group G59 are pleiotropically deficient in respiratory chain components and in mitochondrial ATPase. This phenotype has been shown to be a consequence of mutations in a nuclear gene coding for mitochondrial leucyl-tRNA synthetase. The structural gene (MSL1) coding for the mitochondrial enzyme has be...