Amitriptyline hydrochloride is a highly permeable active pharmaceutical ingredient (API). The function of these drugs is to block the reuptake of the neurotransmitters, norepinephrine and serotonin in the central nervous system. The nano-sized Amitriptyline (AT) imprinted polymer particles were synthesized successfully. The nanoparticles were characterized by Fourier transform infrared spectros...

A comprehensive understanding of ROS (reactive oxygen species)-dependent cellular interaction requires the previously unmet ability to simultaneously monitor the intra- and extra-cellular environments. The present review assesses the potential of novel electrochemical and fluorescent-based nanosensor approaches to address the limitations of existing techniques for ROS analysis. Data generated b...

This paper presents a method for extraction and analysis of curve–type structures which consist of disconnected components. Such structures are found in electron–microscopy (EM) images of metal nanograins, which are widely used in the field of nanosensor technology. The topography of metal nanograins in compound nanomaterials is crucial to nanosensor characteristics. The method of completing su...

Quantum dots-based DNA array, 13electrochemical coding, 14 and.Evaluation of: Zhang CY, Yeh HC, Kuroki MT, Wang TH: Single-quantumdot-based DNA nanosensor. Single Quantum-dot-based Aptameric Nanosensor for Cocaine. Aptamers are single-stranded RNA or DNA molecules with ligand-binding.MS-qFRET: A quantum dot-based method for analysis of DNA methylation. Associated with labeled-MSP products that ...

The revelation of protein-protein interactions is one of the main preoccupations in the eld of proteomics. Nanoplasmonics has emerged as an attractive surface-based technique because of its ability to sense protein binding under physiological conditions in a label-free manner. Here, we present a detailed experimental study of the use of aperiodic photonic nanocavities for plasmonic Surface Enha...

We present molecular dynamics friction calculations for confined hydrocarbon solids with molecular lengths from 20 to 1400 carbon atoms. Two cases are considered: a) polymer sliding against a hard substrate, and b) polymer sliding on polymer. In the first setup the shear stresses are relatively independent of molecular length. For polymer sliding on polymer the friction is significantly larger,...

AbstractIn this paper the problem of designing a polymer repeat unit with fine–tuned or optimized thermophysical and mechanical properties is addressed. The values of these properties are estimated using group contribution methods based on the number and type of the molecular groups participating in the polymer repeat unit. By exploiting the prevailing mathematical features of the structure–pro...

Nanoparticles are increasingly popular choices for labeling and tracking cells in biomedical applications such as cell therapy. However, all current types of nanoparticles fail to provide real-time, noninvasive monitoring of cell status and functions while often generating false positive signals. Herein, a nanosensor platform to track the real-time expression of specific biomarkers that correla...