The urgent need of neuraminidase inhibitors (NI) has provided an impetus for understanding the structure requisite at molecular level. Our search for selective inhibitors of neuraminidase has led to the identification of pharmacophoric requirements at various positions around acyl thiourea pharmacophore. The main objective of present study is to develop selective NI, with least toxicity and dru...

The urgent need of neuraminidase inhibitors (NI) has provided an impetus for understanding the structure requisite at molecular level. Our search for selective inhibitors of neuraminidase has led to the identification of pharmacophoric requirements at various positions around acyl thiourea pharmacophore. The main objective of present study is to develop selective NI, with least toxicity and dru...

The identification of the efficiency of some mtDNA genes of Mus musculus species complex (house mouse) for biosystematics research was studied in this approach. Recent studies have made use of different mitochondrial genes including NADH dehydrogenase genes, cytochrome b gene, cytochrome oxidase genes, D-loop region and whole mtDNA genome to study the house mouse species. Usage of each of these...

candida exists as a normal flora on skin and mucosa. the prevalence of candida-induced infections specially mucosal and vaginal infections have been raised in the world in last decade due to increase in predisposing factors. c.albicans is the major etiological agent of candidiasis, but infections due to other species have been increasing. the aim of this study was to determine candida species b...

background: ovine babesiosis is the most important haemoparasitic tick-borne disease of small ruminants in iran caused by babesia ovis, b. motasi, and b. crassa . the aim of this study was to characterize the species of ovine babesia species isolated from different geographical region of iran. methods: one hundred fifty four blood samples collected from animals, which demonstrated the pale muco...

background: babesia is blood-tissue parasite, which are transmitted by hard ticks from ixodidae family. the parasite is the cause of babesiosis among ruminants. babesia is as one of main fatal factors among livestock in endemic regions such as iran. the aim of this study was to investigate babesia spp infection using microscopic and molecular methods among small ruminants in mazandaran and gole...

some yeast species play important roles in biological control of some fruits’ post harvest infections. for instant, candida, rhodotorula and pichia species employed in biological control of such post harvest diseases as blue mold (penicillium expansum), and also grey mold (botrytis mali) in apple. species identification of yeasts is some most essential part of the related research activities. d...

nosema is a genus of microsporidia, which have significant negative impacts on honeybees. the aim of this study is the epidemiological evaluation and molecular characterization of nosema spices in various counties of east-azerbaijan province (northwest of iran). 387 samples were collected from colonies maintained in various counties of east-azerbaijan province. samples after preparation were...

background and purpose: by using advanced detection/identification methods, the list of emerging uncommon opportunistic yeast infections is rapidly expanding worldwide. our aim in the present study was sequence-based species delineation of previously unidentified yeasts obtained from a clinically yeast collection. materials and methods: a total of twenty three out of the 855 (5.7%) yeast isolat...

background : in this study, we used both its1 and its2 for molecular identification of fasciola species. methods : the region between 18s and 28s of ribosomal dna was used in pcr-rflp method for molecular identification of fasciola species. ninety trematodes of fasciola were collected during abattoir inspection from livers of naturally infected sheep and cattle from khorasan, east azerbaijan, a...