Mutational activation of cytokine receptors has been described in solid cancers but has not been generally known to drive acute leukemia. We have recently described a subgroup of acute lymphoblastic leukemia characterized by an aberrant expression of the receptor to the cytokine thymic stromal lymphopoietin (TSLP). This receptor is a heterodimer of CRLF2 and IL7RA. In addition to its aberrant e...

background and objectives: rapid, accurate and cost effective diagnosis of infectious and non infectious diseases is an essential step for treatment process. nowadays, in line with scientific progression in molecular biology, genetics and biochemistry which are based on biotechnology and genetic engineering aspects, new branch of medicine entitled molecular medicine is being derived. it can be ...

Geoffrey Currie Society of Nuclear Medicine and Molecular Imaging , 2020, 248 pages, $109 The new Pharmacology Primer for Medications in Medical is a timely much-needed book nuclear medicine technologists students. author this book, Currie,

Abstract In vivo molecular imaging is having a great potential that will have an impact on the medicine by detecting diseases in early stages like screening, identifying extent of disease, selecting disease- and patient-specific therapeutic treatment which be hallmark personalized medicine, for directed targeted therapy, also measuring molecular-specific effects treatment. Currently, most commo...

a Translational Cardiology, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden b Vascular Surgery, Center for Molecular Medicine, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden c William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London, United Kingdom d...

1 Department of Molecular Medicine and Surgery, Neurogenetics Division, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden, 2 Department of Clinical Science, Intervention and Technology, Division of Renal Medicine, Karolinska Institutet, Stockholm, Sweden, 3 Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden, and 4 D...