نتایج جستجو برای: monophosphoryl lipid a
تعداد نتایج: 13481193 فیلتر نتایج به سال:
A 3-year prospective post marketing survey on the safety of the recently developed ultrashort pre-seasonal subcutaneous immunotherapy (uSCIT-MPL4) with pollen allergoids adjuvanted with monophosphoryl lipid A was performed. A total of 510 patients received uSCIT-MPL4, 61% for grass, 35.7% for birch, 13.2% for parietaria and 3% for other pollens (ragweed, mugwort, and olive). A total of 3308 inj...
Abbreviations: AE, adverse event; ANOVA, analysis of variance; ATP, according-to9 protocol; CHMP, Committee for Medicinal Products for Human Use; CI, confidence 10 interval; CMI, cell-mediated immune; CS, circumsporozoite; ELISA, enzyme-linked 11 immunosorbent assay; EMA, European Medicines Agency; GMT, geometric mean titer; 12 HBs, hepatitis B surface antigen; HIV, human immunodeficiency virus...
Endotoxin extracted from the heptose-less mutant of Salmonella typhimurium was hydrolyzed in 0.1 N HCl in methanol/water (1:1, v/v) at 100 degrees C to yield lipid A, which was then fractionated on a Sephadex LH-20 column to yield a major monophosphoryl lipid A fraction. The monophosphoryl lipid A was further fractionated by preparative thin layer chromatography. This process yielded three majo...
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