The absorption and fluorescence spectra of phenylcoumarin and cyanophenylbenzocoumarin-3carboxylates 6a-f and 9a-e have been investigated in chloroform, acetonitrile and ethanol. The substituting groups with varying electron donating ability such as N,N-diethyl amine and morpholine at 7-position, in phenylcoumarin-3-carboxylate 6a-f exhibits fluorescence at a longer wavelength i.e. 420-460 nm i...

The effects of local anesthetics were examined on a family of transiently expressed neuronal calcium channels. Fomocaine, a local anesthetic containing a morpholine ring, preferentially blocked (Y,~ channels (Ki = 100 PM), and had a lower affinity (3to 15fold) for (Y,~, (Y,~, and cz,c channels. Block was incompletely reversible, followed I:1 kinetics, and did not affect steady-state inactivatio...

Protonation of gossypol Schiff bases (S1 and S2), possessing different numbers of basic N-atoms, was studied using potentiometric, spectroscopic, ESI MS and PM5 methods. Titration of S1 and S2 with HClO(4), monitored by the FT-IR and (1)H NMR, indicated that the change from the enamine-enamine into the protonated imine-imine tautomeric form occurs at different Schiff base-H(+) ratio. The FT-IR ...

Auxins, such as indole-3-acetic acid (IAA), are important in plant germination and growth, while physiological polyamines, such as putrescine, are involved in cell proliferation and differentiation, and their concentrations increase during germination. In this work, novel indole amides were synthesized in good yields by monoacylation of morpholine and unprotected symmetrical diamines with indol...

monohydrate. Corrigendum Ana C. Mafud* and Maria Teresa Prado Gambardella Instituto de Fı́sica de São Carlos, Universidade de São Paulo, Av. Trabalhador Sãocarlense, 400, Caixa Postal 369, 13566-590 São Carlos, SP, Brazil, and Instituto de Quı́mica de São Carlos, Universidade de São Paulo, Av. Trabalhador Sãocarlense, 400, Caixa Postal 369, 13566-590 São Carlos, SP, Brazil Correspondence e-mail: ...

In title mol-ecule, C(11)H(11)F(3)N(2)O(2), the central -N-C(=O)-N- unit is essentially planar [maximum deviation = 0.013 (2) Å] and forms a dihedral angle of 57.33 (9)° with the benzene ring. The morpholine ring is in a chair conformation. In the crystal, mol-ecules are linked into chains along [001] by N-H⋯O hydrogen bonds.