In this study, we compared the blood oxygen level-dependent (BOLD) signal changes between intragastric load of monosodium L-glutamate (MSG) and inosine monophosphate (IMP), which elicit the umami taste. An intragastric load of 30 mM IMP or 60 mM MSG induced a BOLD signal increase in several brain regions, including the nucleus of the solitary tract (NTS), lateral hypothalamus (LH), and insular ...

In the Western world, consumers have only recently learned to discriminate the Umami taste, although they have enjoyed its contribution to the palatability of traditional dishes for centuries. The flavor enhancing properties of MSG have been scientifically investigated in European subjects. By adding MSG to such foods as soups, their content in sodium can be decreased without altering palatabil...

Monosodium glutamate (MSG) is a salt form of a non-essential amino acid commonly used as a food additive for its unique flavour enhancing qualities. Since the first description of the 'Monosodium glutamate symptom complex', originally described in 1968 as the 'Chinese restaurant syndrome', a number of anecdotal reports and small clinical studies of variable quality have attributed a variety of ...

Monosodium Glutamate (MSG) is one of the world’s most widely used food additives. Its toxic effects have been shown in numerous animal studies, however in most of them, the method of administration and the doses were not similar to human MSG intake. In this paper we review animal and human studies in which MSG effects on central nervous system, adipose tissue and liver, reproductive organs and ...

: Please see related articles and author responses: http://www.nutritionandmetabolism.com/content/9/1/50http://www.nutritionandmetabolism.com/content/10/1/10http://www.nutritionandmetabolism.com/content/10/1/13 ABSTRACT: The article entitled "Monosodium glutamate (MSG) intake is associated with the prevalence of metabolic syndrome in a rural Thai population", concluded that higher amounts of in...

3GHr. The stirnuhis duration was 300ns and the profile duration, which corresponds to the time for which the scattering parameters measurements are performed during the stimulus duration, was 25011s. The maximum stable gain MSG was determined under different pulsed conditions at I' ds = 10V (Fig. 4). At room temperature in class B for the quiescent hias point, the MSG was -4dB. If the device wa...

Glutamate is the most abundant excitatory neurotransmitter in the central nervous system, and is stored and released by both neurons and astrocytes. Despite the important role of glutamate as a neurotransmitter, high levels of extracellular glutamate can result in excitotoxicity and apoptosis. Monosodium glutamate (MSG) is a naturally occurring sodium salt of glutamic acid that is used as a fla...

The objective of this study was to assess the effect of monosodium glutamate (MSG) on broiler performance, blood chemistry and the brain tissues. A total of 120 day-old Lohman broiler chicks were randomly divided into four groups, with 3 replicates (30 birds per treatment). Four approximately isonitrogenous and isocaloric diets with different levels of MSG viz . 0, 0.25, 0.5 and 1.0% were formu...

Glutamate is thought to serve as a special signal for gut functions. We investigated the effects of monosodium l-glutamate (MSG) on gastric emptying and duodenal motility. Ten healthy male volunteers underwent rapid magnetic resonance imaging (MRI) of the abdomen. Coronal images were successively acquired after ingestion of liquid meal (200 kcal in 200 mL: 9 g protein, 28.4 g carbohydrate, 5.6 ...

BACKGROUND Excessive dietary sodium intake causes several diseases, such as hypertension, cardiovascular and renal disease, etc. Hence, reducing sodium intake has been highly recommended. In this study the effect of monosodium glutamate (MSG), as an umami substance, on saltiness and sodium reduction was investigated. METHODS AND RESULTS The trained panellists were presented with basic spicy s...