three separate experiments were conducted to investigate micropropagation of four pear cultivars. in the first trial, the effect of four cultural media (ms, ms/2, msn/2 and mql) were compared on such traits as shoot length, shoot number and color of leaf. from among the media, ms/2 and msn/2 resulted in the most shoot proliferation and the longest shoots respectively. ms medium produced green d...

Calcium phosphate was encapsulated into mesoporous silica nanoparticles (MSN). The effect of pH on the structure and morphology MSN release calcium from investigated. Epoxy coatings with (3 wt%) non-encapsulated wt% 5 were formulated their anti-corrosive performance evaluated by open circuit potential (OCP) electrochemical impedance spectroscopy (EIS) techniques. Results showed that encapsulati...

The advancements in nanoscience have brought attention to the potential of utilizing nanoparticles as carriers for oral insulin administration. This study aims investigate effectiveness synthesized polymeric mesoporous silica (MSN) and their interactions with IR through in-silico docking. Diabetic rats were treated various MSN samples, including pure MSN, Amin-grafted MSN/PEG/Insulin (AMPI), Al...

• The effect of point defects on the electronic and magnetic properties MoSi 2 N 4 monolayer was investigated. H, O, F atoms are considered as adsorbed atoms; As, Ge, P, O substitutional doped single double vacancies typical defects. H adsorption O/P structures shows reversible n–p conduction type switching. Single Si well Si+N vacancy cases structures, while Mo is a semiconductor. two dimensio...

Even though cancer treatment has improved over the recent decades, still more specific and effective treatment concepts are mandatory. Surgical removal is not always possible, metastases are challenging and chemo- and radiotherapy can not only have severe side-effects but also resistances may occur. To cope with these challenges more efficient therapies with fewer side-effects are required. One...

The aim of this study was to evaluate the in vitro and in vivo biocompatibility of artificial bone based on vancomycin loaded mesoporous silica nanoparticles and calcium sulfate composites. In vitro cytotoxicity tests by cholecystokinin octapeptide (CCK-8) assay showed that the 5%Van-MSN-CaSO4 and Van-CaSO4 bone cements were cytocompatible for mouse osteoblastic cell line MC3T3-E1. The microsco...

In this study, a mesoporous silica nanoparticle (MSN)-based nerve growth factor (NGF) delivery system has been successfully embedded within an electroactive polypyrrol (Ppy). The spherical particles with approximately 100 nm diameter possess a large surface-to-volume ratio for the entrapment of NGF into the pores of MSNs while retaining their bioactivity. Direct incorporation of MSN-NGF within ...

Kalirin-7 (Kal7), the major kalirin isoform in adult brain, plays a key role in the formation of dendritic spines in hippocampal/cortical neurons. Its role in the GABAergic medium spiny neurons (MSNs) of the nucleus accumbens (NAc) and striatum, the areas known to play a key role in the common reward pathway, is not as well understood. Although Kal7 expression in mouse NAc increased in response...

Nuclear translocation, driven by the motility apparatus consisting of the cytoplasmic dynein motor and microtubules, is essential for cell migration during embryonic development. Bicaudal-D (Bic-D), an evolutionarily conserved dynein-interacting protein, is required for developmental control of nuclear migration in Drosophila. Nothing is known about the signaling events that coordinate the func...

Objective. To compare ultrasound-guided miniscalpel-needle (UG-MSN) release versus ultrasound-guided dry needling (UG-DN) for chronic neck pain. Methods. A total of 169 patients with chronic neck pain were randomized to receive either UG-MSN release or UG-DN. Before treatment and at 3 and 6 months posttreatment, pain was measured using a 10-point visual analogue scale (VAS). Neck function was e...