نتایج جستجو برای: mthyl cyanoacetate

تعداد نتایج: 140  

Journal: :Acta poloniae pharmaceutica 2012
Mohammad Mumtaz Alam Mymoona Akhter Asif Husain Akranth Marella Om Prakash Tanwar Rahmat Ali Syed Misbahul Hasan Harish Kumar Rashiduddin Haider Mohammad Shaquiquzzaman

Thirteen new 6-(1-H-indole-2-yl)-4-oxo-2-[2-(substituted-benzylidene)-hydrazinyl]-4,5-dihydropy-rimidine-5-carbonitrile derivatives were synthesized. The title compounds, hydrazones, were synthesized by reaction of hydrazine group of 2-hydrazinyl-4-(1-H-indole-2-yl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile (2) with different substituted aromatic aldehydes using a mixture (2:8, v/v) of glacial...

Journal: :Acta poloniae pharmaceutica 2014
Omiama M Abdel Hafez Mahmoud I Nassar Salah M El-Kousy Ayman F Abdel-Razik M M Atalla Sherien Mai M El-Ghonemy

3-Acetyl-4-hydroxycoumarin (2) was reacted with some aldehydes (4-chlorobenzaldehyde, 4-bromobenzaldehyde, 5-methylfurfural) to afford the chalcones (3a-c). Cyclization of these chalcones with malononitrile in the presence of ammonium acetate afforded pyridine carbonitriles (4a-c), while the cyclization reaction of chalcones (3a-c) with ethyl cyanoacetate afforded the oxopyridine carbonitriles ...

Journal: :Journal of The Iranian Chemical Society 2022

Abstract A new series of pyridine-2-one and pyrazole derivatives were designed synthesized based on cyanoacrylamide containing 2,4-dichlro aniline 6-methyl 2-amino pyridine as an aryl group. Condensation 3a–d with different active methylene (malononitrile, ethyl cyanoacetate cyanoacetamide, acetoacetate) in the presence piperidine basic catalyst afforded corresponding pyridinone 4a–c , 5 9 13 ....

Journal: :Acta pharmaceutica 2013
Wagnat Wahba Wardakhan Nahed Nasser Eid El-Sayed Rafat Milad Mohareb

The reaction of cyclopentanone with cyanoacetylhydrazine gave 2-cyano-2-cyclopentylideneacetohydrazide (1). Treatment of compound 1 with elemental sulphur in the presence of triethylamine afforded 2-amino-5,6-dihydro- -4H-cyclopenta[b]thiophene-3-carbohydrazide (2), which in-turn formed the corresponding intermediate diazonium salt. The latter was coupled with either ethyl cyanoacetate or ethyl...

Journal: :ACS Organic & Inorganic Au 2023

Designing efficient, economical heterogeneous catalysts for the Knoevenagel condensation reaction is highly significant owing to importance of products in industries as well pharmaceutics. Herein, we have designed and synthesized biguanidine-functionalized basic magnetically retrievable cobalt ferrite nanoparticles (CFNPs) synthesis using benzaldehydes active methylene compounds (malononitrile/...

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