Human coronavirus (HCoV) accounts for 15-30% of common colds, but only one case report has described the effect of a coronavirus infection, that was asymptomatic, on human respiratory epithelium. The authors examined the effects of infection with HCoV on ciliary structure and function in healthy volunteers infected by intranasal inoculation with HCoV 229E. A further four volunteers were sham in...

Background Primary ciliary dyskinesia (PCD) is an inherited disorder where dyskinetic cilia cause impaired mucociliary clearance (MC) of upper and lower airways. Airway movement can be indirectly tested in vivo after administration a radiolabeled tracer to the airways for assessment pulmonary MC or nose assessing Nasal (NMC). With this study we aimed investigate NMC as quantifiable outcome para...

a 5-month old puppy with muco-cutaneous lesions in the chin, around lips and eyes was exam­ined physically and microscopically for leishmaniasis. muco-cutaneous lesions containing a large num­ber of amastigotes of leishmania spp. were observed . amastigotes were also detected in liver and spleen of the puppy. the animal was positive with dipstick rk39 kit and high level of anti- leishmania anti...

P rimary ciliary dyskinesia (PCD; Immotile cilia syndrome; OMIM 242650) is an autosomal recessive disorder resulting from dysmotility of cilia and sperm flagella. Cilia and flagella function either to create circulation of fluid over a stationary cell surface or to propel a cell through fluid. 3 These related structures are highly complex organelles composed of over 200 different polypeptides. ...

The saccharin test was carried out in a randomly selected sample of schoolchildren (142 boys and 153 girls, age range 11-14 years) to determine the variability and reproducibility of the test and to assess whether it could be used as a screening test for nasal mucociliary clearance. Nasal mucociliary clearance times were analysed according to clinical history (asthma, rhinitis, asthma with rhin...