Hellin (1895) published evidence indicating that the relative frequencies of multiple births conform to a simple mathematical relationship which may be expressed thus: The frequency of triplet maternities is equal to the square of the frequency of twin maternities, and the frequency of quadruplet maternities is equal to its cube. Stated in general terms, if f is the frequency of twin litters, t...

PURPOSE The recent trends of multiple births (MBs) conceived by assisted reproductive technology (ART) in Korea were analyzed as well as the relationship with maternal age, especially advanced maternal age. METHODS Data were obtained from the Korean Statistical Information Service and annual ART reports from the ART committee of the Korean Society of Obstetrics and Gynecology. RESULTS MBs i...

Trends in the civil registration of fetal death in multiple gestations that has occurred before, but expelled from the womb after, 24 weeks' gestation are examined using England and Wales 1993-2004 registration obtained from the Office for National Statistics. Count was made of fetal death registrations in which fetus papyraceous, fetal death before 24 weeks' gestation or fetocide before 24 wee...

Background: FIVCAT.NET is the registry of human assisted reproductive techniques (ART) in Catalunya to which all authorised centres are obliged to declare their activities. The Background of the present study is to describe the data on effectiveness of the ART in Catalunya over the period 2001-2005 and to compare our findings with other similar registries. Materials and Methods: The data were o...

IMPORTANCE Maternal micronutrient deficiencies may adversely affect fetal and infant health, yet there is insufficient evidence of effects on these outcomes to guide antenatal micronutrient supplementation in South Asia. OBJECTIVE To assess effects of antenatal multiple micronutrient vs iron-folic acid supplementation on 6-month infant mortality and adverse birth outcomes. DESIGN, SETTING, ...

This paper is the first in a three-part series on preterm birth, which is the leading cause of perinatal morbidity and mortality in developed countries. Infants are born preterm at less than 37 weeks' gestational age after: (1) spontaneous labour with intact membranes, (2) preterm premature rupture of the membranes (PPROM), and (3) labour induction or caesarean delivery for maternal or fetal in...

Multiple pregnancies (twin, triplet, and higher-order pregnancy) are associated with an increased risk of resultant preterm and low birth weight infants. The increase of multiple pregnancies for several decades in Japan has been an important consideration in bed allocation planning for neonatal intensive care unit (NICU). The guideline of the Japan Society of Obstetrics and Gynecology (JSOG) in...

Multiple pregnancies have increased from 9 per 1000 pregnancies in the 1970s to 14 per 1000 pregnancies. Multiple births account for 10% of perinatal deaths (8% of fetal deaths and 14% of neonatal deaths). Compared to singletons births, the perinatal mortality rate is four times higher in twins, and nine times higher in multiple births of a higher order. The cerebral palsy rate among survivors ...

Objectives Caesarean section (CS) can be life-saving for both mother and child, but in Nigeria the CS rate remains low, at 2.7% of births. We aimed to estimate early neonatal mortality according obstetric risk socio-economic background identify factors associated with CS. Methods used 2018 Demographic Health Survey, encompassing 33 924 live births within last 5 years, (ENMR) by group, informed ...