Deformable image registration (DIR) has potential to enable novel approaches in radiotherapy (RT) such as dose accumulation, online adaptive planning, and response monitoring. Although DIR is predominantly formulated as a single-objective optimization problem, its inherent nature is multi-objective, i.e., there are multiple, conflicting objectives that need to be optimized simultaneously. A maj...

incorporation of functional foods and nutraceuticals such as carotenoids which suffer from poor water solubility and low bioavailability into nano-sized delivery systems can improve their solubility, stability and oral bioavailability. the aim of this study was to prepare β-carotene nanodispersion and investigate the effects of preparation parameters by means of response surface methodology usi...

conclusions we found ccd and rsm very effective in optimizing hib culture conditions, and hib biomass production was greatly influenced by ph and incubation temperature. therefore, optimization of the growth factors to maximize hib production can lead to 1) an increase in bacterial biomass and prp productions, 2) lower vaccine prices, 3) vaccination of more susceptible populations, and 4) lower...

because of high cost of drilling and analysis of samples, it needs to predict gold and silvers based on pathfinder such as as, sb, cd, pb and zn and decrease the cost and time exploration project implementation. in this paper, the model based on a multilayer perceptron artificial neural network (mlp-ann) optimized by invasive weed optimization algorithm (iwo) to predict of gold and silver in za...

Low-cost and power efficient finite impulse response (FIR) designs are presented using the concept of faithfully rounded truncated multipliers. Here we consider the optimization of bit width and hardware resources without abdication of the frequency response and output signal precision in the process of accumulation of filter computations. Non uniform coefficient quantization with proper filter...

In this article, multiple-product PVRP with pickup and delivery that is used widely in goods distribution or other service companies, especially by railways, was introduced. A mathematical formulation was provided for this problem. Each product had a set of vehicles which could carry the product and pickup and delivery could simultaneously occur. To solve the problem, two meta-heuristic methods...

in this paper, a novel approach for multi response optimization is presented. in the proposed approach, response variables in treatments combination occur with a certain probability. moreover, we assume that each treatment has a network style. because of the probabilistic nature of treatment combination, the proposed approach can compute the efficiency of each treatment under the desirable reli...