We describe a small, chronically implantable microwire array for obtaining long-term unit recordings from the cortex of unrestrained nonhuman primates. After implantation, the depth of microwires can be individually adjusted to maintain large-amplitude action potential recordings from single neurons over many months. We present data recorded from the primary motor cortex of two monkeys by auton...

ABSTRACT Despite advocacy of landscape approaches in cultural resource management (CRM) and critiques the site concept, CRM data collection methods western United States continue to focus on individual archaeological sites as units observation, analysis, management. The transect-recording unit (TRU) method strikes a balance between conventional site-based recording site-less survey by dividing ...

OBJECTIVE To objectively record sleep patterns in intensive care unit patients using the Bispectral Index as an electroencephalographic measure of sleep and to determine if the sleep pattern is correlated with various clinical factors. METHODS Adult intensive care patients were recruited who were in the recovery phase of their illness and on minimal sedation. The sleep pattern was examined us...

Visual processing depends critically on the receptive field (RF) properties of visual neurons. However, comprehensive characterization of RFs beyond the primary visual cortex (V1) remains a challenge. Here we report fine RF structures in secondary visual cortex (V2) of awake macaque monkeys, identified through a projection pursuit regression analysis of neuronal responses to natural images. We ...

Continuous EEG monitoring in the intensive care unit (ICU) is superficially similar to that which occurs in the epilepsy monitoring unit, but it also presents unique technical challenges. ICU monitoring imposes an expectation of reliability on EEG recording equipment exceeding that which may be demanded by other settings; performance requirements may also differ. Reliable network connectivity b...

A method is described by which a single shaft multiwire microelectrode can be fabricated efficiently. The resulting electrode can be attached to a commercial microdrive and used for single neuronal unit recording from one or more tracks in deep brain structures of anesthetized or awake animals. The electrode consists of a 30 gauge stainless steel cannula through which multiple strands of 13 mic...

Chronic multichannel neural recording has emerged as a powerful technique for studying dynamic brain function. In many experimental paradigms, it is important that the same neurons be recorded from day to day. The objective of this study was to develop methods for tracking the recorded neural population over time through analysis of unit waveforms, principle component clusters and response prop...