During July 2015–May 2016, a mumps outbreak occurred at the University of Iowa, which is located in Johnson County (1). A total of 301 cases of mumps were diagnosed among students. To characterize the outbreak, the Johnson County Public Health Department, the Iowa Department of Public Health, and the University of Iowa, with assistance from CDC, conducted an investigation through telephone inte...

PURPOSE Mumps vaccine has not been included in the routine national immunization program in Japan, leading to low vaccine coverage rates and periodic epidemics approximately every 5 years. Our hospital (a secondary community hospital in Japan) experienced an increased number of mumps-related complications with a nationwide epidemic in 2016. Using previously reported data and mumps-related cases...

Johnstone, J. A., Ross, C. A. C., and Dunn, M. (1972). Archives of Disease in Childhood, 47, 647. Meningitis and encephalitis associated with mumps infection: a 10-year survey. During the 10-year period 1960-69, 137 patients in Ruchill Hospital were diagnosed by clinical and laboratory findings as mumps meningitis. Parotitis was detected in only 51 (37%). There was a male preponderance, 97: 40....

The expression of mumps virus nucleocapsid protein in yeast Pichia pastoris was investigated. Viral nucleocapsid proteins usually elicit a strong long-term humoral immune response in patients and experimental animals. Therefore, the detection of antibodies specific to mumps virus nucleoprotein can play an important role in immunoassays for mumps diagnosis. For producing a high-level of recombin...

It is well known that unilateral profound sensorineural hearing loss is caused by mumps; however, bilateral deafness is rare. Herein we report a case of bilateral profound hearing loss caused by mumps infection in a four-year-old boy. Labyrinthitis due to the mumps virus was suspected. His verbal understanding was poor, and he completely stopped talking. He was soon fitted with a hearing aid, b...

The epidemiology of mumps in India and the magnitude of the problem are not fully appreciated(2). Outbreaks occur at interval of 5-10yrs(2). Mumps continue to occur in epidemic proportions despite the availability of an effective vaccine. Finland became the first documented country to be free of indigenous mumps and rubella with the use of national 2 dose trivalent MMR vaccination program, free...

INTRODUCTION: Neglected infectious diseases like mumps may be opportunistic in controlled areas with low vaccine coverage, particularly in developed and emerging countries. METHODS: A retrospective analysis of mumps-related data from 2001 to 2016 for São Paulo State, Brazil was conducted. RESULTS: From 2014 to 2015, there was an increase of 82% in reported mumps cases in São Paulo, with pre...

We present here the complete genome sequences of three mumps virus (MuV) strains isolated from patients who tested positive for the mumps virus during a mumps outbreak in Springdale, AR (USA), in 2016. The virus genomes, sequenced with Oxford Nanopore technology, belong to genotype G and have an average length of 15,342 nucleotides (nt).

Abstract Mumps is nowadays re-emerging despite vaccination. The contribution of T cell immunity to protection against mumps has not been clearly defined. Previously, we described a set 41 peptides that were eluted from human leukocyte antigen (HLA) class I molecules virus (MuV)-infected cells. Here, confirmed immunogenicity five novel HLA-B*07:02- and HLA-A*01:01-restricted MuV epitopes this pe...

This talk focuses on the direct solution of large complex indefinite unsymmetric systems, that arise in acoustic, vibro-acoustic and aero-acoustic simulations. These systems are structurally symmetric and may contain some large dense blocks, e.g. due to the selection of hybrid modal/physical representations in the model. The first part of the talk gives an overview of the experienced MUMPS capa...