نتایج جستجو برای: n methyl n nitrosourea
تعداد نتایج: 1047583 فیلتر نتایج به سال:
Different biological aspects of a novel 2-chloroethyl nitrosourea derived from cysteamine, N'-(2-chloroethyl)-N-[2-(methylsulfinyl)ethyl]-N'- nitrosourea (CMSOEN2), were studied. Drug-induced cytotoxic effects, uptake kinetics, DNA damage, and O6-alkylguanine-DNA alkyltransferase activity were determined in 3 melanoma cell lines: the murine B16 and 2 human metastatic-derived cell lines (M4 Beu ...
In N-methyl-N-nitrosourea (MNU)-induced colon cancer modeling in rats, it was aimed to evaluate the regressive effect of grayanotoxin-rich Turkish mad honey and 5-fluorouracil (5-FU), separately together. Study groups were control group (CG), (CCG), 5-Flourouracil (FUG), (HG), 5-FU combined (FU-HG). WBC, lymphocyte, eosinophil, basophil, serum LDH, TOS, total protein values determined rats CCG ...
Adult male Fischer rats were exposed to a necrogenic dose (200 mg/kg) of diethylnitrosamine or to nonnecrogenic doses of N-methyl-N-nitrosourea, 1,2-dimethylhydrazine, or benzo(a)pyrene following partial hepatectomy or sham hepatectomy. This treatment by itself led to no hepatocellular carcinomas by 8 to 18 months, except in animals given N-methyl-N-nitrosourea, which showed a 30% incidence by ...
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