Abstract:
 Aim: to evaluate the bone healing in failed endodontically treated teeth after surgical removal of periapical lesions and placement hydroxyapatite (HA), nanohydroxyapatite (nHA) a combination with platelet rich fibrin (PRF) periapically. Subjects methods: study was conducted on twenty-four patients having radiolucency single rooted teeth. The selected were divided into three gro...