Photodynamic therapy (PDT) is a concept based on selective activation by light of drugs called photosensitizers (PS) leading to reactive oxygen species production responsible for cell destruction. Mechanisms photodynamic reaction and photo-destruction following direct or indirect mechanisms will be presented as well PS classification, from first generation molecules developed in the 1960 s thir...

From recombinant insulin to monoclonal antibodies, proteins have become essential drugs in the therapeutic arsenal and respond a broad spectrum of diseases. While commercially available an extracellular activity, intracellular targets can be powerful alternative treat many pathologies such as cancers immune disorders, but also infectious Nevertheless, enter cell reach target organelle or molecu...

Non-viral gene therapy based on silencing with small interfering RNA (siRNA) has attracted great interest over recent years. Among various types of cationic complexation agents, amino acid-based surfactants have been recently explored for nucleic acid delivery due to their low toxicity and high biocompatibility. Monoolein (MO), in turn, used as helper lipid liposomal systems its ability form in...

Abstract Background Skin cancers are among the widely prevalent forms of cancer worldwide. The increasing industrialization and accompanied environmental changes have further worsened skin statistics. stern topical barrier although difficult to breach is a little compromised in pathologies like cancer. therapeutic management has moved beyond chemotherapy surgery. Main body abstract quest for ma...