HYPOTHESIS The sensitivity of sestamibi scanning techniques used for preoperative localization in primary hyperparathyroidism is a function of the parameters of image acquisition and processing. DESIGN Criterion standard vs optimized technique. SETTING Tertiary referral center. PATIENTS One hundred forty-eight consecutive patients with primary hyperthyroidism were analyzed. Under the init...

An inauspicious start to 2009, unfortunately. This issue may seem a little thinner than others we've recently published, as 4 articles that were previously accepted and scheduled for publication in this issue will not appear. We continue to screen all figures from accepted manuscripts, and we continue to find irregularities. In several cases, the alterations in the figures led to the discovery ...

T he actin-binding protein vinculin leads a double life in a cell, bolstering contacts with other cells and strengthening adhesions to its substrate. Bays et al. now explain what differentiates the protein for its distinct roles, revealing that cells phosphorylate vinculin molecules in cell–cell junctions (1). When cells are stretched, squeezed, or bent, they don’t just sit there passively. The...

There are two main modalities of communication between neurons, known as electrical and chemical synaptic transmission. Despite striking differences in their underlying mechanisms, new evidence suggests that the formation of electrically and chemically mediated synapses is under common regulatory processes.

Given the beneets of sharing a cache among large user populations, Internet Service Providers will likely enter into peering agreements to share their caches. This position paper describes our approach for inter-proxy cooperation in this environment. While existing cooperation models focus on maximizing global hit ratios, values of cache hits in our environment depend on peering agreements and ...

In a retrospective review by Hannan et al. (1) in this issue of JACC: Cardiovascular Interventions, 30-day readmission rates for percutaneous coronary intervention (PCI) patients were analyzed using both clinical and administrative datasets to determine overall readmission rates, planned or staged readmissions, and a determination of predictors for unstaged readmissions. The 30-day readmission ...

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