background nasal colonization of healthy children with staphylococcus aureus is an important risk factor for different infections. detection of colonized individuals with methicillin resistant s. aureus (mrsa) and its eradication is the proper prevention strategy for infection spread in the community and health-care centers. objectives the aim of this study was to determine the prevalence, asso...

Mupirocin is a topically applied drug that is very active in the eradication of nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA). However, studies designed to compare mupirocin treatment with other antimicrobial regimens are lacking. We therefore conducted an open, prospective, randomized, controlled trial to compare the efficacy and safety of mupirocin versus those of oral ...

BACKGROUND Methicillin resistant Staphylococcus aureus (MRSA) poses a threat to patient safety and public health. Understanding how MRSA is acquired is important for prevention efforts. This study investigates risk factors for MRSA nasal carriage among patients at an eastern North Carolina hospital in 2011. METHODS Using a case-control design, hospitalized patients ages 18 - 65 years were enr...

Staphylococcus aureus is a frequent cause of infections in both the community and hospital. Worldwide, the increasing resistance of this pathogen to various antibiotics complicates treatment of S aureus infections. Effective measures to prevent S aureus infections are therefore urgently needed. It has been shown that nasal carriers of S aureus have an increased risk of acquiring an infection wi...

55% of a sample of patients in a rural community, and 76% of a sample of patients and staff in the local district hospital were found to be nasal carriers for Staphylococcus aureus. The in vitro antibiotic susceptibility patterns of 46 strains of S. aureus isolated in nasal carriers as well as of 43 strains in community-acquired skin infections were characterised. High levels of resistance were...

BACKGROUND Staphylococcus aureus is an important human opportunistic pathogen residing on skin and mucosae of healthy people. Pigs have been identified as a source of human colonization and infection with methicillin-resistant Staphylococcus aureus (MRSA) and novel measures are needed to control zoonotic transmission. A recent longitudinal study indicated that a minority of pigs characterized b...

OBJECTIVES This study aimed to evaluate the persistence of nasal carriage of Staphylococcus aureus, methicillin-resistant S. aureus and multidrug-resistant S. aureus over 14 days of follow-up among industrial hog operation workers in North Carolina. METHODS Workers anticipating at least 24 h away from work were enrolled June-August 2012. Participants self-collected a nasal swab and completed ...

BACKGROUND A major risk factor for the development of surgical site infections is Staphylococcus aureus carriage. Compared with non-carriers, S. aureus carriers have up to a 14-fold greater risk for post-surgical infections. Pre-operative screening for S. aureus carriage is controversial. Yet, targeted screening in high-risk patients or from clinically relevant sites may be beneficial. We aimed...

Female sex hormones have been related to nasal Staphylococcus aureus carriage in healthy individuals; however, whether nasal staphylococcal carriage varies by menstrual cycle phase remains unknown.We sampled anterior nares of female healthcare workers twice per week for 6 consecutive menstrual cycles. We used mixed-effects Poisson regression models to determine whether intermittent carriage was...